CAS 445-14-7

5-Chloro-2-(trifluoromethyl)benzenamine

Description:

5-Chloro-2-(trifluoromethyl)benzenamine, with the CAS number 445-14-7, is an organic compound characterized by the presence of both a chloro group and a trifluoromethyl group attached to a benzene ring. This compound features an amine functional group, which contributes to its reactivity and potential applications in various chemical reactions. The chloro substituent typically enhances the electrophilic character of the aromatic ring, while the trifluoromethyl group is known for its electron-withdrawing properties, influencing the compound's overall electronic distribution. This combination of substituents can affect the compound's solubility, boiling point, and reactivity, making it of interest in synthetic organic chemistry and potentially in pharmaceuticals or agrochemicals. Additionally, the presence of fluorine atoms often imparts unique properties, such as increased lipophilicity and metabolic stability. Safety data should be consulted for handling this compound, as halogenated amines can pose health risks.

Formula: C₇H₅ClF₃N

InChI: InChI=1S/C7H5ClF3N/c8-4-1-2-5(6(12)3-4)7(9,10)11/h1-3H,12H2

InChI key: InChIKey=GXMFVMMXHKXSBI-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=C(N)C=C(Cl)C=C1

Synonyms:

• Benzenamine, 5-chloro-2-(trifluoromethyl)-
• 5-Chloro-2-(trifluoromethyl)benzenamine
• 5-Chloro-α,α,α-trifluoro-o-toluidine
• o-Toluidine, 5-chloro-α,α,α-trifluoro-
• 2-(Trifluoromethyl)-5-chloroaniline

2-Amino-4-chlorobenzotrifluoride

CAS: 445-14-7

Formula: C₇H₅ClF₃N

Purity: 97%

Color and Shape: Liquid

Molecular weight: 195.5695

Ref: IN-DA00DBQ8

5-Chloro-2-(trifluoromethyl)aniline

CAS: 445-14-7

5-Chloro-2-(trifluoromethyl)aniline

Formula: C₇H₅ClF₃N

Purity: 95%

Color and Shape: brown liquid

Molecular weight: 195.57g/mol

Ref: 54-PC49064

2-Amino-4-chlorobenzotrifluoride

CAS: 445-14-7

Formula: C₇H₅ClF₃N

Purity: 98%

Color and Shape: Liquid

Molecular weight: 195.57

Ref: 10-F077921

2-Amino-4-chlorobenzotrifluoride

Controlled Product

CAS: 445-14-7

Applications 2-Amino-4-chlorobenzotrifluoride is a potent activator of the histone acetyltransferase (HAT) of p300.
References Mantelingu, K., et al.: J. Phys. Chem. B, 111, 4527-4534 (2007)

Formula: C₇H₅ClF₃N

Color and Shape: Neat

Molecular weight: 195.57

Ref: TR-A595415