CAS 445-27-2

2′-Fluoroacetophenone

Description:

2′-Fluoroacetophenone, with the CAS number 445-27-2, is an organic compound belonging to the class of ketones. It features a fluoro group attached to the aromatic ring of acetophenone, which contributes to its unique chemical properties. This compound typically appears as a colorless to pale yellow liquid with a characteristic odor. It is moderately soluble in organic solvents such as ethanol and ether but has limited solubility in water due to its hydrophobic aromatic structure. The presence of the fluorine atom enhances its reactivity, making it useful in various chemical syntheses, particularly in the production of pharmaceuticals and agrochemicals. 2′-Fluoroacetophenone can undergo typical electrophilic aromatic substitution reactions, and its reactivity can be influenced by the electron-withdrawing nature of the fluorine substituent. Safety precautions should be taken when handling this compound, as it may pose health risks if inhaled or ingested. Overall, 2′-Fluoroacetophenone is a valuable compound in organic synthesis and research applications.

Formula: C₈H₇FO

InChI: InChI=1S/C8H7FO/c1-6(10)7-4-2-3-5-8(7)9/h2-5H,1H3

InChI key: InChIKey=QMATYTFXDIWACW-UHFFFAOYSA-N

SMILES: C(C)(=O)C1=C(F)C=CC=C1

Synonyms:

• 1-(2-Fluorophenyl)ethan-1-one
• 1-(2-Fluorophenyl)ethanone
• 2'-Fluoro acetophenone
• 2-Fluorophenyl methyl ketone
• Acetophenone, 2′-fluoro-
• Ethanone, 1-(2-fluorophenyl)-
• Methyl 2-fluorophenyl ketone
• NSC 88297
• o-Fluoroacetophenone
• 2′-Fluoroacetophenone
• 2-Fluoroacetophenone

2'-Fluoroacetophenone

CAS: 445-27-2

Formula: C₈H₇FO

Purity: >97.0%(GC)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 138.14

Ref: 3B-F0364

2'-Fluoroacetophenone

CAS: 445-27-2

Formula: C₈H₇FO

Purity: 95%

Color and Shape: Liquid

Molecular weight: 138.1390

Ref: IN-DA003GA2

Vonoprazan Impurity 31

CAS: 445-27-2

Formula: C₈H₇FO

Molecular weight: 138.14

Ref: 4Z-V-051033

2'-Fluoroacetophenone, min. 98%

CAS: 445-27-2

Formula: C₈H₇FO

Purity: min. 98%

Color and Shape: clear colorless liquid

Molecular weight: 138.14

Ref: 08-09-0079

2-Fluoroacetophenone

CAS: 445-27-2

Formula: C₈H₇FO

Molecular weight: 138.14

Ref: 7W-GK4223

2′-Fluoroacetophenone

CAS: 445-27-2

Formula: C₈H₇FO

Purity: 97%

Color and Shape: Clear

Molecular weight: 138.141

Ref: 10-F001616

2'-Fluoroacetophenone

CAS: 445-27-2

2'-Fluoroacetophenone

Formula: C₈H₇FO

Purity: 98%

Color and Shape: clear. almost colourless liquid

Molecular weight: 138.14g/mol

Ref: 54-PC3360

2'-Fluoro acetophenone

CAS: 445-27-2

2'-Fluoro acetophenone is a chiral compound that can be used as an organic overlayer to control the enantiomeric purity of organic reactions. The cavity in the molecule provides an electronic interaction that stabilizes the radical form of 2'-fluoroacetophenone. This cavity also allows for hydrogenation reactions to occur more quickly and with less byproduct formation than other types of reactions. Additionally, this reaction occurs at a lower temperature than most other reactions, making it optimal for industrial production.

Formula: C₈H₇FO

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 138.14 g/mol

Ref: 3D-FF33640

2'-Fluoroacetophenone

Controlled Product

CAS: 445-27-2

Impurity Vonoprazan Impurity 31
Applications 2'-Fluoroacetophenone (Vonoprazan Impurity 31)

Formula: C₈H₇FO

Color and Shape: Neat

Molecular weight: 138.14

Ref: TR-F587073

Vonoprazan Impurity 119

CAS: 445-27-2

Formula: C₈H₇FO

Molecular weight: 138.14

Ref: ST-EA-CP-V14084

2'-Fluoroacetophenone, 97%

CAS: 445-27-2

2'-Fluoroacetophenone is used as starting reagent in the synthesis of ascididemin. It is used to produce 1-(2-piperidin-1-yl-phenyl)-ethanone by reaction with piperidine. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and la

Formula: C₈H₇FO

Purity: 97%

Color and Shape: Clear colorless, Liquid

Molecular weight: 138.14

Ref: 02-A15128