CAS 445430-58-0

N1-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine

Description:

N1-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine, with the CAS number 445430-58-0, is a synthetic organic compound characterized by its complex structure, which includes an imidazoquinoxaline moiety and an ethanediamine functional group. This compound is notable for its potential biological activity, particularly in the context of medicinal chemistry and pharmacology. The presence of the dimethyl groups on the imidazo ring may influence its lipophilicity and interaction with biological targets. The ethanediamine portion contributes to its ability to form hydrogen bonds, which can enhance its solubility and reactivity. As a member of the imidazoquinoxaline family, it may exhibit properties relevant to cancer research, as some derivatives in this class have shown antitumor activity. However, detailed studies on its specific biological effects, toxicity, and pharmacokinetics are essential for understanding its potential applications in drug development. Overall, this compound represents a fascinating area of study within the field of organic and medicinal chemistry.

Formula: C₁₄H₁₇N₅

InChI: InChI=1S/C14H17N5/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18)

InChI key: InChIKey=PSPFQEBFYXJZEV-UHFFFAOYSA-N

SMILES: CC=1N2C=3C(N=C(NCCN)C2=NC1)=CC=C(C)C3

Synonyms:

• 1,2-Ethanediamine, N1-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)-
• 1,2-Ethanediamine, N-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)-
• N1-(1,8-Dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine

IKK Inhibitor III, BMS-345541

CAS: 445430-58-0

Formula: C₁₄H₁₇N₅

Purity: %

Color and Shape: Solid

Molecular weight: 255.3183

Ref: IN-DA00DB56

BMS-345541

CAS: 445430-58-0

BMS-345541

Purity: ≥98%

Molecular weight: 255.32g/mol

Ref: 54-BUP12746

BMS-345541

CAS: 445430-58-0

BMS-345541 (IKK Inhibitor III) is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 μM and 4 μM, respectively.

Formula: C₁₄H₁₇N₅

Purity: 99.36% - 99.74%

Color and Shape: Solid

Molecular weight: 255.32

Ref: TM-T6326

IKK Inhibitor III, BMS-345541

CAS: 445430-58-0

IKK Inhibitor III, BMS-345541, is a selective small-molecule inhibitor, which is synthesized through chemical processes within specialized laboratories. This compound specifically targets the IκB kinase (IKK) enzymes, inhibiting their function in the NF-κB signaling pathway. By binding to the ATP-binding site of the IKK complex, BMS-345541 effectively prevents the phosphorylation and degradation of IκB proteins. This interruption leads to reduced NF-κB activation, thereby modulating the expression of various genes involved in inflammatory and immune responses.

Formula: C₁₄H₁₇N₅·2C₂HF₃O₂

Purity: Min. 95%

Molecular weight: 483.36 g/mol

Ref: 3D-VSA43058