CAS 446-08-2

2-Amino-5-fluorobenzoic acid

Description:

2-Amino-5-fluorobenzoic acid, with the CAS number 446-08-2, is an aromatic amino acid derivative characterized by the presence of an amino group (-NH2) and a fluorine atom attached to a benzoic acid structure. This compound features a carboxylic acid group (-COOH) that contributes to its acidic properties. The fluorine substituent at the 5-position of the benzene ring influences the compound's reactivity and polarity, potentially enhancing its biological activity. 2-Amino-5-fluorobenzoic acid is typically a white to off-white crystalline solid, soluble in polar solvents such as water and alcohols, and exhibits moderate stability under standard conditions. It is often utilized in pharmaceutical research and synthesis, particularly in the development of various biologically active compounds. The presence of both the amino and carboxylic acid functional groups allows for diverse chemical reactivity, making it a valuable intermediate in organic synthesis and medicinal chemistry. Safety data should be consulted for handling and potential hazards associated with this compound.

Formula: C₇H₆FNO₂

InChI: InChI=1/C7H6FNO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,9H2,(H,10,11)/p-1

InChI key: InChIKey=FPQMGQZTBWIHDN-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(N)C=CC(F)=C1

Synonyms:

• 2-Amino-5-(fluoromethyl)benzoic acid
• 2-Amino-5-Fluorobenzoate
• 2-Amino-5-Fluorobenzoic Acid 99+%
• 2-Amino-5-fluoroBenzoicacid97.
• 2-Amino-5-fluorobenzoic
• 2-Amino-5-fluorobenzoic Acid, 5-FAA
• 2-Amino-5-fluorobenzoic acid (5-Fluoroanthranilic acid)
• 2-Amino-5-fluorobenzoic acid 97.5%
• 5-Fluoro-2-aminobenzoic acid
• 5-Fluoroanthranilic Acid
• 5-Fluoroanthranilic Acid 98+%
• 5-FluoroanthranilicAcid/2-Amino-5-FluorobenzoicAcid
• Anthranilic acid, 5-fluoro-
• Aurora Ka-5382
• Benzoic acid, 2-amino-5-fluoro-
• Buttpark 19\04-54
• NSC 513308
• Rarechem Al Bo 2236
• 2-Amino-5-fluorobenzoic acid
• 5-FAA
• 2-Amino-5-fluorobenzoic acid, 98+%

2-Amino-5-fluorobenzoic acid, 97%

CAS: 446-08-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₆FNO₂

Purity: 97%

Color and Shape: Pale cream to cream to brown or yellow, Crystals or powder or crystalline powder

Molecular weight: 155.13

Ref: 02-B21458

2-Amino-5-fluorobenzoic Acid

CAS: 446-08-2

Formula: C₇H₆FNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 155.1264

Ref: IN-DA003GGZ

2-Amino-5-fluorobenzoic acid

CAS: 446-08-2

Formula: C₇H₆FNO₂

Molecular weight: 155.13

Ref: 7W-GM1551

2-Amino-5-fluorobenzoic Acid

CAS: 446-08-2

Formula: C₇H₆FNO₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Brown powder to crystal

Molecular weight: 155.13

Ref: 3B-F0396

2-Amino-5-fluorobenzoic acid

CAS: 446-08-2

2-Amino-5-fluorobenzoic acid

Formula: C₇H₆FNO₂

Purity: 98%

Color and Shape: pale yellow solid

Molecular weight: 155.13g/mol

Ref: 54-PC1071F

5-Fluoroanthranilic Acid

Controlled Product

CAS: 446-08-2

Applications Used for the counterselection of TRP1, a commonly used genetic marker in the yeast Saccharoyces Cerevisiae. An antimetabolite for the tryptophan pathway in yeast, and is toxic by virtue of its antimetabolite conversion to 5-Fluorotryptophan. It can be used for the selection of tryptophan auxotroophs.
References Toyn, J.H., et al.: Yeast, 16, 553, 560 (2000)

Formula: C₇H₆FNO₂

Color and Shape: Neat

Molecular weight: 155.13

Ref: TR-F587750

5-Fluoroanthranilic acid

CAS: 446-08-2

5-Fluoroanthranilic acid is a synthetic compound that belongs to the class of anthranilic acid derivatives. It inhibits the growth of bacteria by reacting with the hydroxyl group on the bacterial cell wall and binding to its target, which is a cellular component found in Gram-positive bacteria. The molecular modeling and gene analysis have shown that this compound has an optimal reaction at pH 8.5, which is not in accordance with the natural environment of bacteria. 5-Fluoroanthranilic acid has been shown to have anticancer activity against wild-type cells but not against resistant mutants.

Formula: C₇H₆FNO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 155.13 g/mol

Ref: 3D-FF11395

2-Amino-5-fluorobenzoic acid

CAS: 446-08-2

Formula: C₇H₆FNO₂

Purity: 97%

Color and Shape: Solid, Crystalline Powder or Fibers or Powder

Molecular weight: 155.128

Ref: 10-F003126