CAS 4463-44-9

Xylene cyanol

Description:

Xylene cyanol, also known as xylene cyanol FF, is a synthetic dye commonly used in molecular biology and biochemistry as a tracking dye in gel electrophoresis. It is characterized by its deep blue color and is soluble in water and various organic solvents. The chemical structure of xylene cyanol consists of a phenolic compound with a sulfonic acid group, which contributes to its solubility and stability in aqueous solutions. This dye has a relatively low toxicity profile, making it suitable for laboratory use, although safety precautions should still be observed. Xylene cyanol migrates at a specific rate during electrophoresis, allowing researchers to estimate the size of nucleic acid fragments in agarose or polyacrylamide gels. Its application extends beyond molecular biology, as it is also utilized in various industrial processes, including textile dyeing and as a pH indicator. Overall, xylene cyanol is a versatile compound with significant utility in both research and industrial contexts.

Formula: C₂₅H₂₈N₂O₇S₂·Na

InChI: InChI=1S/C25H28N2O7S2.Na/c1-5-26-20-9-7-17(11-15(20)3)25(18-8-10-21(27-6-2)16(4)12-18)19-13-22(28)24(36(32,33)34)14-23(19)35(29,30)31;/h7-14,26,28H,5-6H2,1-4H3,(H,29,30,31)(H,32,33,34);

InChI key: InChIKey=JKPDSWLBCLGXEQ-UHFFFAOYSA-N

SMILES: C(C1=C(S(=O)(=O)O)C=C(S(=O)(=O)O)C(O)=C1)(C2=CC(C)=C(NCC)C=C2)=C3C=C(C)C(=NCC)C=C3.[Na]

Synonyms:

• 1,3-Benzenedisulfonic acid, 4-((4-(ethylamino)-3-methylphenyl)(4-(ethylimino)-3-methyl-2,5-cyclohexadien-1- ylidene)methyl)-6-hydroxy-, monosodium salt
• 1,3-Benzenedisulfonic acid, 4-[[4-(ethylamino)-3-methylphenyl][4-(ethylimino)-3-methyl-2,5-cyclohexadien-1-ylidene]methyl]-6-hydroxy-, sodium salt (1:1)
• 4-{(E)-[4-(ethylamino)-3-methylphenyl][(4E)-4-(ethylimino)-3-methylcyclohexa-2,5-dien-1-ylidene]methyl}-6-hydroxybenzene-1,3-disulfonic acid
• 4-{(Z)-[4-(ethylamino)-3-methylphenyl][(4E)-4-(ethylimino)-3-methylcyclohexa-2,5-dien-1-ylidene]methyl}-6-hydroxybenzene-1,3-disulfonate
• Cyanol FF
• Toluene-2,4-disulfonic acid, α-[4-(ethylamino)-m-tolyl]-α-[4-(ethylimino)-3-methyl-2,5-cyclohexadien-1-ylidene]-5-hydroxy-, monosodium salt
• Xylene cyanol
• sodium hydride - 4-{(Z)-[4-(ethylamino)-3-methylphenyl][(4E)-4-(ethylimino)-3-methylcyclohexa-2,5-dien-1-ylidene]methyl}-6-hydroxybenzene-1,3-disulfonic acid (1:1)
• C.I. 43535

sodium 4-{[4-(ethylamino)-3-methylphenyl][(1Z,4E)-4-(ethylimino)-3-methylcyclohexa-2,5-dien-1-ylidene]methyl}-2-hydroxy-5-sulfobenzenesulfonate

CAS: 4463-44-9

Formula: C₂₅H₂₇N₂NaO₇S₂

Purity: 80%

Color and Shape: Solid

Molecular weight: 554.6108

Ref: IN-DA00DEQ5

Xylene Cyanol FF

CAS: 4463-44-9

Xylene Cyanol FF

Purity: ≥80%

Molecular weight: 554.61g/mol

Ref: 54-OR1030065

Xylene cyanol

CAS: 4463-44-9

Xylene cyanol is a chemical compound that belongs to the group of phenols. It has been shown to be active in vitro against human skin cancer cells, and induces cell lysis. Xylene cyanol has also been found to bind to the BCR-ABL kinase domain, which is an enzyme that plays a crucial role in the development of leukemia and other autoimmune diseases. Xylene cyanol binds to dna binding domains on the protein surface and forms an adduct with bcr-abl kinase, which inhibits its activity. This inhibition prevents activation of this enzyme and leads to cell death by preventing DNA synthesis.

Formula: C₂₅H₂₇N₂O₇S₂•Na

Purity: Min. 90%

Color and Shape: Powder

Molecular weight: 554.61 g/mol

Ref: 3D-FX158238