CAS 447406-78-2

Sodelglitazar

Description:

Sodelglitazar is a synthetic compound classified as a dual PPAR (peroxisome proliferator-activated receptor) agonist, specifically targeting PPAR-α and PPAR-γ. This dual activity is significant in the context of metabolic disorders, particularly type 2 diabetes and dyslipidemia, as it can help improve insulin sensitivity and lipid profiles. The chemical structure of Sodelglitazar includes functional groups that facilitate its interaction with the PPAR receptors, promoting the regulation of genes involved in glucose and lipid metabolism. Its pharmacological profile suggests potential benefits in managing metabolic syndrome, although clinical efficacy and safety profiles are essential for therapeutic applications. As with many investigational drugs, ongoing research is crucial to fully understand its mechanisms, benefits, and any potential side effects. The compound is identified by its CAS number 447406-78-2, which serves as a unique identifier in chemical databases, aiding in the tracking of its research and development status.

Formula: C₂₃H₂₁F₄NO₃S₂

InChI: InChI=1S/C23H21F4NO3S2/c1-12-9-15(6-8-18(12)31-22(3,4)21(29)30)32-11-19-13(2)28-20(33-19)16-7-5-14(10-17(16)24)23(25,26)27/h5-10H,11H2,1-4H3,(H,29,30)

InChI key: InChIKey=ZUGQWAYOWCBWGM-UHFFFAOYSA-N

SMILES: FC1=C(C=2SC(CSC3=CC(C)=C(OC(C(O)=O)(C)C)C=C3)=C(C)N2)C=CC(C(F)(F)F)=C1

Synonyms:

• 2-[4-[[[2-[2-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methyl]sulfanyl]-2-methylphenoxy]-2-methylpropanoic acid
• 2-[4-[[[2-[2-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]-2-methylpropanoic acid
• Gw 677954
• Propanoic acid, 2-[4-[[[2-[2-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]-2-methyl-
• Sodelglitazar

Sodelglitazar

CAS: 447406-78-2

Sodelglitazar, a PPAR agonist, is used potentially for the treatment of hyperlipidemia and type 2 diabetes.

Formula: C₂₃H₂₁F₄NO₃S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 499.54

Ref: TM-T28825