CAS 4491-19-4

Indaconitine

Description:

Indaconitine, with the CAS number 4491-19-4, is a chemical compound classified as an alkaloid derived from the plant genus Aconitum, commonly known as monkshood or wolfsbane. This substance is characterized by its complex molecular structure, which includes multiple rings and functional groups typical of alkaloids. Indaconitine exhibits potent pharmacological properties, particularly as a neurotoxin, affecting the nervous system by blocking sodium channels, which can lead to significant physiological effects. It is known for its potential use in traditional medicine, although its toxicity poses serious risks, including respiratory failure and cardiac complications. Due to its hazardous nature, indaconitine is handled with caution in laboratory and clinical settings. Its solubility in organic solvents and limited solubility in water are notable physical properties, influencing its behavior in biological systems. Research continues to explore its mechanisms of action and potential therapeutic applications, while also emphasizing the importance of safety and toxicity management when dealing with such compounds.

Formula: C₃₄H₄₇NO₁₀

InChI: InChI=1S/C34H47NO10/c1-7-35-16-31(17-40-3)21(37)13-22(41-4)34-20-14-32(39)23(42-5)15-33(45-18(2)36,25(28(34)35)26(43-6)27(31)34)24(20)29(32)44-30(38)19-11-9-8-10-12-19/h8-12,20-29,37,39H,7,13-17H2,1-6H3/t20-,21-,22+,23+,24-,25+,26+,27-,28-,29-,31+,32+,33-,34+/m1/s1

InChI key: InChIKey=PHDZNMWTZQPAEW-IOZYTHHVSA-N

SMILES: O(C)[C@@H]1[C@@]23[C@]4([C@](COC)(CN(CC)[C@@]2([C@]([C@@H]4OC)([C@]5(OC(C)=O)[C@@]6([C@]3(C[C@@](O)([C@@H]6OC(=O)C7=CC=CC=C7)[C@@H](OC)C5)[H])[H])[H])[H])[C@H](O)C1)[H]

Synonyms:

• (3Alpha,6Alpha,14Alpha,16Beta)-8-(Acetyloxy)-20-Ethyl-3,13-Dihydroxy-1,6,16-Trimethoxy-4-(Methoxymethyl)Aconitan-14-Yl Benzoate
• 15-Deoxyaconitine
• 2H-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine, aconitane-3,8,13,14-tetrol deriv.
• Acetylbenzoylpseudaconine
• Acetylbenzoylpseudoaconine
• Aconitane-3,8,13,14-tetrol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1α,3α,6α,14α,16β)-
• Indaconitine

(1α,3α,6α,14α,16β)-8-Acetate-14-benzoate-20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-aconitane-3,8,13,14-tetrol

CAS: 4491-19-4

Formula: C₃₄H₄₇NO₁₀

Purity: 98%

Color and Shape: Solid

Molecular weight: 629.7377

Ref: IN-DA00DB8S

Indaconitine

CAS: 4491-19-4

Indaconitine

Purity: ≥98%

Molecular weight: 629.74g/mol

Ref: 54-BUP03354

Indaconitine

CAS: 4491-19-4

Formula: C₃₄H₄₇NO₁₀

Molecular weight: 629.75

Ref: 7W-GY1370

Indaconitine

CAS: 4491-19-4

Formula: C₃₄H₄₇NO₁₀

Purity: 95%~99%

Molecular weight: 629.747

Ref: BP-BP0763

Indaconitine

CAS: 4491-19-4

Indaconitine is isolated from the rhizome of the Aconitum plant.

Formula: C₃₄H₄₇NO₁₀

Purity: 99.32%

Color and Shape: Solid

Molecular weight: 629.74

Ref: TM-T6S1879

Indaconitine

CAS: 4491-19-4

Indaconitine is a highly potent alkaloid, which is a naturally occurring compound extracted from the Aconitum species, commonly known as monkshood or wolfsbane. This alkaloid is primarily found in the roots and tubers of these plants, which have been historically noted for their toxic and medicinal properties.

Formula: C₃₄H₄₇NO₁₀

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 629.74 g/mol

Ref: 3D-FI65788

Indaconitine (>90%)

Controlled Product

CAS: 4491-19-4

Applications Indaconitine is used in preparation of aconine and pseudaconine, their NMR spectra, and effect of solvents on conformation as reactant/reagent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Deng, H.Y., et al.: Nat. Prod. Commun. 9, 785-786 (2014)

Formula: C₃₄H₄₇NO₁₀

Purity: >90%

Color and Shape: Neat

Molecular weight: 629.74

Ref: TR-I499760