CAS 4494-26-2
:2'-deoxy-5-formyluridine
Description:
2'-Deoxy-5-formyluridine is a nucleoside derivative of uridine, characterized by the presence of a formyl group at the 5-position of the uracil base and a deoxyribose sugar. This compound is notable for its role in biochemical research, particularly in studies related to RNA and DNA modifications. It exhibits properties typical of nucleosides, including the ability to participate in hydrogen bonding due to the presence of nitrogen and oxygen atoms in its structure. The formyl group contributes to its reactivity, allowing it to engage in various chemical reactions, such as condensation and oxidation. 2'-Deoxy-5-formyluridine can be utilized in the synthesis of modified nucleotides and nucleic acids, making it valuable in the development of therapeutic agents and molecular probes. Its solubility in polar solvents and stability under physiological conditions further enhance its utility in biochemical applications. Overall, this compound serves as an important tool in molecular biology and medicinal chemistry, facilitating the exploration of nucleic acid functions and interactions.
Formula:C10H12N2O6
InChI:InChI=1/C10H12N2O6/c13-3-5-2-12(10(17)11-9(5)16)8-1-6(15)7(4-14)18-8/h2-3,6-8,14-15H,1,4H2,(H,11,16,17)/t6-,7+,8+/m0/s1
InChI key:InChIKey=MVORBLZUGBSUNB-XLPZGREQSA-N
SMILES:O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=C(C=O)C(=O)N1
Synonyms:- 1-(2-Deoxypentofuranosyl)-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidine-5-Carbaldehyde
- 5-Formyl-2′-deoxyuridine
- 5-Formyldeoxyuridine
- 5-Fromyl-2'-Deoxyuridine
- 5-Pyrimidinecarboxaldehyde, 1-(2-Deoxypentofuranosyl)-1,2,3,4-Tetrahydro-2,4-Dioxo-
- 5-Pyrimidinecarboxaldehyde, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-
- 5-Pyrimidinecarboxaldehyde, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-
- NSC 148297
- Thymidine, α-oxo-
- Uridine, 2'-Deoxy-5-Formyl-
- α-Oxothymidine
- 5-Pyrimidinecarboxaldehyde, 1-(2-deoxy-β-D-ribofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-
- 5-FORMYL-DU
- 2'-Deoxy-5-formyluridine
- 5-Pyrimidinecarboxaldehyde, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,2,3,4-tetrahydro-2,4-dioxo-
- 5-formyl-2'-dU
- 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2,4-dioxopyrimidine-5-carbaldehyde
- 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyriMidine-5-carbaldehyde
- See more synonyms
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Found 7 products.
5-Formyl-2'-deoxyuridine
CAS:Formula:C10H12N2O6Purity:95%Color and Shape:SolidMolecular weight:256.21211-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde
CAS:Controlled Product<p>Applications 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde (cas# 4494-26-2) is a useful research chemical.<br></p>Formula:C10H12N2O6Color and Shape:NeatMolecular weight:256.212'-Deoxy-5-formyluridine
CAS:<p>2'-Deoxy-5-formyluridine (2DFO) is a nucleobase analogue that inhibits the enzymatic activity of DNA glycosylases, which are enzymes that remove sugar residues from damaged DNA. 2DFO has been shown to induce apoptosis in cancer cells by inhibiting DNA synthesis and promoting oxidative damage to the cell's DNA. 2DFO has also been shown to inhibit the growth of DU-145 cells in vitro and in vivo models. This drug was found to be more effective at preventing metastasis of colorectal cancer when it was administered with a platinum-based chemotherapy drug.</p>Formula:C10H12N2O6Purity:Min. 95 Area-%Color and Shape:White Off-White PowderMolecular weight:256.21 g/mol1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde
CAS:Formula:C10H12N2O6Purity:95%Molecular weight:256.2141-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde
CAS:Formula:C10H12N2O6Molecular weight:256.21
