CAS 4499-40-5

Oxtriphylline

Description:

Oxtriphylline, with the CAS number 4499-40-5, is a pharmaceutical compound primarily used as a bronchodilator in the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). It is a xanthine derivative, which means it is structurally related to caffeine and theophylline, and it works by relaxing the smooth muscles of the airways, thereby facilitating easier breathing. Oxtriphylline is known for its ability to enhance respiratory function and improve airflow. The compound is typically administered orally and is available in various formulations, including tablets and syrups. Its pharmacological effects are attributed to its ability to inhibit phosphodiesterase, leading to increased levels of cyclic AMP, which promotes bronchodilation. While generally well-tolerated, potential side effects may include gastrointestinal disturbances, nervousness, and increased heart rate. As with any medication, it is important for patients to follow dosing guidelines and consult healthcare professionals regarding its use, especially in the presence of other medical conditions or medications.

Formula: C₇H₇N₄O₂·C₅H₁₄NO

InChI: InChI=1S/C7H8N4O2.C5H14NO/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;1-6(2,3)4-5-7/h3H,1-2H3,(H,8,9,12);7H,4-5H2,1-3H3/q;+1/p-1

InChI key: InChIKey=RLANKEDHRWMNRO-UHFFFAOYSA-M

SMILES: O=C1C2=C(N(C)C(=O)N1C)N=C[N-]2.C([N+](C)(C)C)CO

Synonyms:

• 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dimethyl-, ion(1-), 2-hydroxy-N,N,N-trimethylethanaminium
• 2-Hydroxy-N,N,N-trimethylethanaminium salt with 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione (1:1)
• Choledyl
• Choledyl SA
• Cholegyl
• Choline Theophyllinate
• Choline, compd. with theophylline
• Choline, compd. with theophylline (1:1)
• Cholinophylline
• Cholintheophyllinat
• Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione (1:1)
• Filoral
• Oxtrimethylline
• Oxtriphylline
• Oxytrimethylline
• Sabidal
• Soliphylline
• Teofilcolina
• Teofilinato De Colina
• Teokolin
• Teovent
• Theophyllinate de choline
• Theophylline cholinate
• Theophylline, compd. with choline
• Theophylline, ion(1-) choline (1:1)
• Theoxylline
• Zy 15061
• Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with 3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione (1:1)
• Sabidal SR
• Bronchodil
• choline theophylline

Oxtriphylline

CAS: 4499-40-5

Theophylline and aminophylline (excluding fenetylline) and their derivatives, salts thereof, not elsewhere specified or included

Formula: C₁₂H₂₁N₅O₃

Color and Shape: White Crystalline Powder

Molecular weight: 283.16444

Ref: 45-1484009

Oxytrimethylline

Controlled Product

CAS: 4499-40-5

Formula: C₇H₇N₄O₂·C₅H₁₄NO

Color and Shape: Neat

Molecular weight: 283.33

Ref: TR-O867275

Oxytrimethylline

Controlled Product

CAS: 4499-40-5

Oxytrimethylline is a theophylline-related drug that is used for chronic pulmonary diseases. Oxytrimethylline is not absorbed well from the gut, so it must be given intravenously to achieve therapeutic concentrations in the blood. Oxytrimethylline has been shown to inhibit the growth of polymorphonuclear leukocytes and human bronchial epithelial cells by inhibiting protein synthesis at the ribosome level. It also has anti-inflammatory effects and may be useful in treating bowel disease and asthma. Slow-release formulations of oxytrimethylline are available for geriatric patients who have difficulty swallowing or have decreased gastrointestinal motility.

Formula: C₁₂H₂₁N₅O₃

Purity: Min. 95%

Molecular weight: 283.33 g/mol

Ref: 3D-EAA49940

Choline theophyllinate

CAS: 4499-40-5

Choline theophyllinate (Oxtriphylline) is the choline salt of theophylline, a small molecule PDE inhibitor that can be used to treat immune system disorders and

Formula: C₁₂H₂₁N₅O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 283.33

Ref: TM-T14958