CAS 450-95-3

2-Fluoro-1-phenylethanone

Description:

2-Fluoro-1-phenylethanone, also known as fluoroacetophenone, is an organic compound characterized by the presence of a fluorine atom attached to the second carbon of a phenyl group adjacent to a carbonyl group (ketone). Its molecular formula is C8H7FO, indicating it contains eight carbon atoms, seven hydrogen atoms, one fluorine atom, and one oxygen atom. This compound typically appears as a colorless to pale yellow liquid with a distinctive aromatic odor. It is soluble in organic solvents such as ethanol and ether but has limited solubility in water. 2-Fluoro-1-phenylethanone is used in organic synthesis and can serve as an intermediate in the production of various pharmaceuticals and agrochemicals. The presence of the fluorine atom can influence the compound's reactivity and biological activity, making it of interest in medicinal chemistry. As with many organic compounds, proper handling and safety precautions are essential due to potential toxicity and environmental impact.

Formula: C₈H₇FO

InChI: InChI=1S/C8H7FO/c9-6-8(10)7-4-2-1-3-5-7/h1-5H,6H2

InChI key: InChIKey=YOMBUJAFGMOIGS-UHFFFAOYSA-N

SMILES: C(CF)(=O)C1=CC=CC=C1

Synonyms:

• 1-Fluoroacetophenone
• 2-Fluoro-1-phenylethanone
• 2-Fluoroacetophenone
• Acetophenone, 2-fluoro-
• Brn 1858991
• Ethanone, 2-fluoro-1-phenyl-
• Ethanone, 2-fluoro-1-phenyl- (9CI)
• Monofluoromethyl phenyl ketone
• Phenacyl fluoride
• alpha-Fluoroacetophenone
• α-Fluoroacetophenone

Phenacyl fluoride

CAS: 450-95-3

Phenacyl fluoride

Formula: C₈H₇FO

Purity: 97%

Color and Shape: off-white fused solid

Molecular weight: 138.14g/mol

Ref: 54-PC7958

2-Fluoro-1-phenylethanone

CAS: 450-95-3

Formula: C₈H₇FO

Purity: 97%

Color and Shape: Solid, Low Melting Solid

Molecular weight: 138.141

Ref: 10-F091880

2-Fluoro-1-phenylethanone

CAS: 450-95-3

2'-Fluoroacetophenone is a fluorinated ketone that has been used as a substrate for hydrogenation, oxidation, and reduction reactions. It has the structural formula C8H6F2O. The chemical shifts of 2'-fluoroacetophenone in its 1H NMR spectrum were observed at 8.78 ppm and 10.14 ppm. The reactivity of this compound is determined by the type of enzyme it is exposed to. For example, 2'-fluoroacetophenone reacts with an oxidase enzyme to form an acetophenone derivative that can be reduced to the corresponding alcohol or oxidized to an acid chloride or ketone. This compound also binds to serotonin receptors and inhibits serotonin reuptake in the brain, which leads to depression-like symptoms in rats after chronic exposure.

Formula: C₈H₇FO

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 138.14 g/mol

Ref: 3D-FF77422