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CAS 4500-70-3

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  • GlcNAc-MurNAc
    Targetmol
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    GlcNAc-MurNAc

    CAS:
    GlcNAc-MurNAc is a disaccharide and mild TLR4 agonist with a Kd of 383 μM for mouse TLR4. It directly binds to TLR4, activating the downstream NF-κB and IRF pathways. Additionally, GlcNAc-MurNAc ameliorates dextran sulfate sodium salt (DSS)-induced colitis in mice through a TLR4-dependent mechanism, making it useful for inflammatory bowel disease research.
    Formula:C19H32N2O13
    Color and Shape:Solid
    Molecular weight:496.46

    Ref: TM-T211496

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