CAS 451-71-8

Glyhexamide

Description:

Glyhexamide, with the CAS number 451-71-8, is a chemical compound that belongs to the class of sulfonylureas, primarily known for its use in the management of diabetes mellitus. It functions as an antihyperglycemic agent, promoting insulin secretion from the pancreas and enhancing the sensitivity of peripheral tissues to insulin. Glyhexamide is characterized by its ability to lower blood glucose levels, making it beneficial for individuals with type 2 diabetes. The compound typically appears as a white to off-white crystalline powder and is soluble in water, which facilitates its absorption in the body. Its mechanism of action involves binding to specific receptors on pancreatic beta cells, leading to increased insulin release in response to glucose. While effective, glyhexamide may also have side effects, including hypoglycemia and gastrointestinal disturbances. As with any medication, it is essential for users to consult healthcare professionals for appropriate dosing and monitoring to ensure safety and efficacy in treatment.

Formula: C₁₆H₂₂N₂O₃S

InChI: InChI=1S/C16H22N2O3S/c19-16(17-14-7-2-1-3-8-14)18-22(20,21)15-10-9-12-5-4-6-13(12)11-15/h9-11,14H,1-8H2,(H2,17,18,19)

InChI key: InChIKey=NFRPNQDSKJJQGV-UHFFFAOYSA-N

SMILES: S(NC(NC1CCCCC1)=O)(=O)(=O)C=2C=C3C(=CC2)CCC3

Synonyms:

• 1-Cyclohexyl-3-(2,3-dihydro-1H-inden-5-ylsulfonyl)urea
• 1-Cyclohexyl-3-(5-indanylsulfonyl)urea
• 1H-Indene-5-sulfonamide, N-[(cyclohexylamino)carbonyl]-2,3-dihydro-
• N-(cyclohexylcarbamoyl)-2,3-dihydro-1H-indene-5-sulfonamide
• N-[(Cyclohexylamino)carbonyl]-2,3-dihydro-1H-indene-5-sulfonamide
• NSC 106960
• Serbose
• Sq 15860
• Subose
• Urea, 1-cyclohexyl-3-(5-indanylsulfonyl)-

Glyhexamide

CAS: 451-71-8

Glyhexamide is a drug that was first used in the 1950s as a metabolic agent for patients with diabetes. It is an analog of meglitinide and has been shown to have antidiabetic and insulin sensitizing properties. Glyhexamide also has the ability to bind to magnesium ions, which may be important in its mechanisms of action. This drug has been shown to improve insulin sensitivity and decrease blood glucose levels in patients with type 2 diabetes mellitus and can be used in combination with other drugs, such as serotonin reuptake inhibitors, for this purpose. Glyhexamide also increases coronary heart disease risk factors by enhancing the effects of insulin on lipids and by increasing the risk of congestive heart failure.

Formula: C₁₆H₂₂N₂O₃S

Purity: Min. 95%

Molecular weight: 322.4 g/mol

Ref: 3D-AAA45171

Glyhexamide

CAS: 451-71-8

Glyhexamide is an effective hypoglycemic compound.

Formula: C₁₆H₂₂N₂O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 322.42

Ref: TM-T13711