CAS 452-35-7

Ethoxzolamide

Description:

Ethoxzolamide is a sulfonamide derivative primarily recognized for its application as a carbonic anhydrase inhibitor. This compound is characterized by its ability to interfere with the enzyme that catalyzes the reversible hydration of carbon dioxide, which plays a crucial role in various physiological processes, including acid-base balance and fluid secretion. Ethoxzolamide is typically presented as a white to off-white crystalline powder, exhibiting moderate solubility in water and organic solvents. Its molecular structure includes a sulfonamide group, which is essential for its biological activity. Ethoxzolamide has been explored for therapeutic uses, particularly in the treatment of conditions such as glaucoma and certain types of edema, due to its diuretic properties. Additionally, it may have applications in managing altitude sickness by promoting bicarbonate excretion. As with many sulfonamides, caution is advised regarding potential allergic reactions and side effects. Overall, Ethoxzolamide's unique mechanism of action and its role in pharmacology make it a compound of interest in medicinal chemistry.

Formula: C₉H₁₀N₂O₃S₂

InChI: InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13)

InChI key: InChIKey=OUZWUKMCLIBBOG-UHFFFAOYSA-N

SMILES: S(N)(=O)(=O)C=1SC=2C(N1)=CC=C(OCC)C2

Synonyms:

• 2-Benzothiazolesulfonamide, 6-ethoxy-
• 6-Ethoxybenzothiazol-2-sulfonamid
• 6-Ethoxybenzothiazole-2-Sulfonamide
• 6-Ethoxybenzothiazole-2-Sulphonamide
• 6-Ethoxyzolamide
• 6-Etoxibenzotiazol-2-Sulfonamida
• Cardrase
• Diuretic C
• Ethamide
• Ethoxyzolamide
• Ethoxzolamide
• Etoxzolamide
• Glaucotensil
• L 643786
• Nsc 10679
• Pnu 4191
• Redupresin
• U 4191

6-ETHOXY-2-BENZOTHIAZOLESULFONAMIDE

CAS: 452-35-7

Formula: C₉H₁₀N₂O₃S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 258.3173

Ref: IN-DA00DEP4

Ethoxzolamide

CAS: 452-35-7

Ethoxzolamide

Purity: ≥95%

Molecular weight: 258.32g/mol

Ref: 54-BUP06765

6-Ethoxy-2-benzothiazolesulfonamide

CAS: 452-35-7

Formula: C₉H₁₀N₂O₃S₂

Molecular weight: 258.32

Ref: 7W-GL6734

Ethoxzolamide

CAS: 452-35-7

Ethoxzolamide (L-643786) is a carbonic anhydrase inhibitor.

Formula: C₉H₁₀N₂O₃S₂

Purity: 98.27% - 99.62%

Color and Shape: Crystals From Ethyl Acetate + Skellysolve B Solid

Molecular weight: 258.32

Ref: TM-T5012

Ethoxzolamide

Controlled Product

CAS: 452-35-7

Applications Ethoxzolamide is used in the treatment of glaucoma, and is also used as a diuretic, acting as a carbonic anhydrase inhibitor.
References Temperini, C. et al.: Bioorg. Med. Chem., 17, 1214 (2009); Garcia-Fernandez, M. et al.: Bioorg. Med. Chem., 21, 6674 (2013);

Formula: C₉H₁₀N₂O₃S₂

Color and Shape: Off-White

Molecular weight: 258.32

Ref: TR-E893000

6-Ethoxy-2-benzothiazolesulfonamide

CAS: 452-35-7

6-Ethoxy-2-benzothiazolesulfonamide is a drug that inhibits carbonic anhydrase, which is an enzyme that catalyzes the conversion of carbon dioxide and water to bicarbonate and hydrogen ions. This drug has been shown to be effective for the treatment of bowel disease in animal models. 6-Ethoxy-2-benzothiazolesulfonamide has also been shown to have inhibitory properties against carbonic anhydrase, which may lead to problems with dehydration.

Formula: C₉H₁₀N₂O₃S₂

Purity: Min. 95%

Molecular weight: 258.32 g/mol

Ref: 3D-FE61560

Ethoxzolamide

CAS: 452-35-7

Color and Shape: Neat

Ref: 61-FOR3082.00