CAS 452-78-8

3-Fluoro-4-methylphenol

Description:

3-Fluoro-4-methylphenol, with the CAS number 452-78-8, is an organic compound that belongs to the class of phenols. It features a fluorine atom and a methyl group attached to a benzene ring, specifically at the 3 and 4 positions, respectively. This compound is characterized by its aromatic structure, which contributes to its stability and reactivity. It typically appears as a colorless to pale yellow liquid or solid, depending on the temperature and purity. The presence of the fluorine atom enhances its chemical properties, making it more polar and potentially increasing its reactivity in nucleophilic substitution reactions. 3-Fluoro-4-methylphenol is soluble in organic solvents and exhibits moderate solubility in water. It is used in various applications, including as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Safety precautions should be taken when handling this substance, as it may pose health risks if ingested or inhaled, and appropriate protective equipment should be used.

Formula: C₇H₇FO

InChI: InChI=1/C7H7FO/c1-5-2-3-6(9)4-7(5)8/h2-4,9H,1H3

InChI key: InChIKey=GJOOCAXPERKNMN-UHFFFAOYSA-N

SMILES: FC1=C(C)C=CC(O)=C1

Synonyms:

• 3-Fluoro-4-cresol
• 3-Fluoro-p-cresol
• 452-78-8
• Phenol, 3-fluoro-4-methyl
• Qr Cf D1
• Qr Cf D1 [Wln]
• p-Cresol, 3-fluoro-
• 3-Fluoro-4-methylphenol
• 3-Fluoro-p-cresol (OH=1)

3-Fluoro-4-methylphenol

CAS: 452-78-8

Formula: C₇H₇FO

Purity: 98%

Color and Shape: Liquid

Molecular weight: 126.1283

Ref: IN-DA003JGD

3-Fluoro-4-methylphenol

CAS: 452-78-8

3-Fluoro-4-methylphenol

Formula: C₇H₇FO

Purity: ≥95%

Color and Shape: Colourless Liquid

Molecular weight: 126.13g/mol

Ref: 54-PC8221

3-Fluoro-p-cresol

CAS: 452-78-8

Formula: C₇H₇FO

Purity: >98.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to lump

Molecular weight: 126.13

Ref: 3B-F0481

3-Fluoro-4-methylphenol

CAS: 452-78-8

3-Fluoro-4-methylphenol is a regiospecific, nature, activating, radiopharmaceutical, which is used in the synthesis of asymmetric formylation reagents. It can be synthesized from nitrobenzene and formaldehyde in the presence of sodium hydroxide. 3-Fluoro-4-methylphenol can be converted to 3-fluoroacetophenone by hydrogenation with palladium on charcoal. This compound has an electron withdrawing group and a nucleophilic group that are activated by a dihedral angle of 30° or less. The nitro group has the ability to accept electrons from other compounds or compounds such as ammonia or amines.

Formula: C₇H₇FO

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 126.13 g/mol

Ref: 3D-FF32979

3-Fluoro-4-methylphenol

CAS: 452-78-8

Formula: C₇H₇FO

Purity: 98%

Color and Shape: Liquid

Molecular weight: 126.13

Ref: 10-F013359