CAS 452-80-2

2-Fluoro-4-methylaniline

Description:

2-Fluoro-4-methylaniline, with the CAS number 452-80-2, is an aromatic amine characterized by the presence of a fluorine atom and a methyl group attached to a benzene ring. This compound features a primary amine functional group (-NH2) that contributes to its reactivity and potential applications in organic synthesis. The fluorine atom, located at the ortho position relative to the amine group, can influence the electronic properties of the molecule, enhancing its nucleophilicity and altering its reactivity in electrophilic aromatic substitution reactions. 2-Fluoro-4-methylaniline is typically a colorless to pale yellow liquid or solid, depending on its purity and temperature. It is soluble in organic solvents and may exhibit moderate toxicity, necessitating careful handling. This compound is often utilized in the synthesis of dyes, pharmaceuticals, and agrochemicals, owing to its ability to serve as a building block in various chemical reactions. As with many aromatic amines, it is important to consider its environmental impact and potential health hazards during use and disposal.

Formula: C₇H₈FN

InChI: InChI=1/C6H5ClFN/c7-5-2-1-4(8)3-6(5)9/h1-3H,9H2

InChI key: InChIKey=ZQEXBVHABAJPHJ-UHFFFAOYSA-N

SMILES: FC1=C(N)C=CC(C)=C1

Synonyms:

• (2-Fluoro-4-methylphenyl)amine
• 2-Fluoro-4-Methyl-Benzenamin
• 2-Fluoro-4-methyl aniline
• 2-Fluoro-4-methylbenzenamine
• 2-Fluoro-P-Toluidin
• 2-Fluoro-P-Toluidine
• 4-Amino-3-Fluorotoluene
• 4-Methyl-2-fluoroaniline
• Benzenamine, 2-fluoro-4-methyl-
• NSC 147489
• p-Toluidine, 2-fluoro-
• 2-Fluoro-4-methylaniline 99%
• NH2=1
• 2-fluoro-4-met
• 2-FLUORO-4-METHYLANILINE
• 2-Fluoro-4-methylaniline99%
• 2-FLUORO-PARATOLUIDINE

2-Fluoro-4-methylaniline, 99%

CAS: 452-80-2

2-Fluoro-4-methylaniline is used in the preparation of 6-chloro-5-fluoroindole via Leimgruber-Batcho reaction. It is also used in the preparation of an (S)-amino alcohol, 2-amino-3-(2-fluoro-4-methylphenyl)-propan-1-ol. This Thermo Scientific Chemicals brand product was originally part of the Alfa A

Formula: C₇H₈FN

Purity: 99%

Color and Shape: Liquid, Clear colorless or yellow to orange or pale red to dark red to pale brown

Molecular weight: 125.15

Ref: 02-A16591

2-Fluoro-4-methyaniline

CAS: 452-80-2

Formula: C₇H₈FN

Purity: 95%

Color and Shape: Liquid

Molecular weight: 125.1435

Ref: IN-DA0033B4

2-Fluoro-4-methylaniline

CAS: 452-80-2

Formula: C₇H₈FN

Molecular weight: 125.15

Ref: 7W-GK8054

2-Fluoro-4-methylaniline

CAS: 452-80-2

2-Fluoro-4-methylaniline

Formula: C₇H₈FN

Purity: 99%

Color and Shape: clear. dark red liquid

Molecular weight: 125.14g/mol

Ref: 54-PC3817KS

2-Fluoro-4-methylaniline

CAS: 452-80-2

Formula: C₇H₈FN

Purity: >97.0%(GC)(T)

Color and Shape: Light yellow to Brown clear liquid

Molecular weight: 125.15

Ref: 3B-F0529

2-Fluoro-4-methylaniline

CAS: 452-80-2

Formula: C₇H₈FN

Purity: 95%

Color and Shape: Liquid

Molecular weight: 125.146

Ref: 10-F001686