CAS 4521-61-3

3,4,5-Trimethoxybenzoyl chloride

Description:

3,4,5-Trimethoxybenzoyl chloride is an organic compound characterized by its benzoyl chloride structure, which features a benzene ring substituted with three methoxy groups at the 3, 4, and 5 positions. This compound is typically a colorless to pale yellow liquid and is known for its reactivity due to the presence of the acyl chloride functional group, making it a useful intermediate in organic synthesis. It is soluble in organic solvents such as dichloromethane and ether but is generally insoluble in water. The presence of the methoxy groups enhances its electron-donating properties, which can influence its reactivity in electrophilic aromatic substitution reactions. 3,4,5-Trimethoxybenzoyl chloride is often utilized in the synthesis of various pharmaceuticals, agrochemicals, and other fine chemicals. However, it should be handled with care due to its potential to cause irritation to the skin and respiratory system, and appropriate safety measures should be taken when working with this compound.

Formula: C₁₀H₁₁ClO₄

InChI: InChI=1S/C10H11ClO4/c1-13-7-4-6(10(11)12)5-8(14-2)9(7)15-3/h4-5H,1-3H3

InChI key: InChIKey=BUHYMJLFRZAFBF-UHFFFAOYSA-N

SMILES: O(C)C1=C(OC)C=C(C(Cl)=O)C=C1OC

Synonyms:

• 3,4,5,-Trimethoxybenzoylchloride
• 3,4,5-Trimethoxybenzoic acid chloride
• 3,4,5-Trimethoxybenzoylchlorid
• Benzoyl chloride, 3,4,5-trimethoxy-
• Chloride 3,4,5-trimethoxybenzoate
• Chlorure de 3,4,5-trimethoxybenzoyle
• Cloruro De 3,4,5-Trimetoxibenzoilo
• Nsc 91023
• Tri-O-methylgalloyl chloride
• Trimethylgalloyl chloride
• 3,4,5-Trimethoxybenzoyl chloride

3,4,5-Trimethoxybenzoyl chloride

CAS: 4521-61-3

Formula: C₁₀H₁₁ClO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 230.6449

Ref: IN-DA00706T

3,4,5-Trimethoxybenzoyl Chloride

CAS: 4521-61-3

3,4,5-Trimethoxybenzoyl Chloride

Purity: 98%

Molecular weight: 230.64g/mol

Ref: 54-OR1010769

3,4,5-Trimethoxybenzoyl Chloride

CAS: 4521-61-3

Formula: C₁₀H₁₁ClO₄

Purity: >97.0%(T)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 230.64

Ref: 3B-T1842

3,4,5-Trimethoxybenzoyl Chloride

Controlled Product

CAS: 4521-61-3

Applications 3,4,5-Trimethoxybenzoyl Chloride is used as a reagent in the synthesis of 2-methyl-8-(3,4,5-trimethoxybenzamido)-1,2,3,4-tetrahydroisoquinoline and its analogs which display great antihypertensive activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mathison, I.W., et al.: J. Med. Chem., 16, 332 (1973)

Formula: C₁₀H₁₁ClO₄

Color and Shape: Neat

Molecular weight: 230.64

Ref: TR-T796225

3,4,5-Trimethoxybenzoyl chloride

CAS: 4521-61-3

Formula: C₁₀H₁₁ClO₄

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 230.64

Ref: 10-F358243

3,4,5-Trimethoxybenzoyl chloride

CAS: 4521-61-3

3,4,5-Trimethoxybenzoyl Chloride is a reactive, active chemical that is used in the synthesis of cytotoxic amides. It is prepared by reacting 3,4,5-trimethoxybenzoic acid with an amine or ammonia in the presence of a base. The reaction yields an amide substituted at the 3- and 4-positions with trimethoxyphenyl groups.

Formula: C₁₀H₁₁ClO₄

Purity: Min. 95%

Molecular weight: 230.64 g/mol

Ref: 3D-EAA52161