Description:3,4,5-Trimethoxybenzoyl chloride is an organic compound characterized by its benzoyl chloride structure, which features a benzene ring substituted with three methoxy groups at the 3, 4, and 5 positions. This compound is typically a colorless to pale yellow liquid and is known for its reactivity due to the presence of the acyl chloride functional group, making it a useful intermediate in organic synthesis. It is soluble in organic solvents such as dichloromethane and ether but is generally insoluble in water. The presence of the methoxy groups enhances its electron-donating properties, which can influence its reactivity in electrophilic aromatic substitution reactions. 3,4,5-Trimethoxybenzoyl chloride is often utilized in the synthesis of various pharmaceuticals, agrochemicals, and other fine chemicals. However, it should be handled with care due to its potential to cause irritation to the skin and respiratory system, and appropriate safety measures should be taken when working with this compound.
Applications 3,4,5-Trimethoxybenzoyl Chloride is used as a reagent in the synthesis of 2-methyl-8-(3,4,5-trimethoxybenzamido)-1,2,3,4-tetrahydroisoquinoline and its …
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