BRD-K20733377, with the CAS number 452350-43-5, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential as a therapeutic agent. While specific characteristics such as its molecular formula, structure, and physical properties may vary, compounds like BRD-K20733377 are often evaluated for their biological activity, solubility, stability, and interaction with biological targets. Typically, such compounds are assessed for their efficacy in inhibiting specific enzymes or pathways relevant to disease processes. Additionally, they may undergo extensive testing for toxicity and pharmacokinetics to determine their suitability for further development as drugs. The compound's role in research may also involve its use as a tool in biochemical assays or as a lead compound for drug discovery. For precise details regarding its characteristics, including its specific molecular structure and biological activity, consulting specialized databases or scientific literature is recommended.

BRD-K20733377

452350-43-5: BRD-K20733377, with the CAS number 452350-43-5, is a chemical compound that has garnered attention in the field of medicinal chemistry, particularly for its potential as a therapeutic agent. While specific characteristics such as its molecular formula, structure, and physical properties may vary, compounds like BRD-K20733377 are often evaluated for their biological activity, solubility, stability, and interaction with biological targets. Typically, such compounds are assessed for their efficacy in inhibiting specific enzymes or pathways relevant to disease processes. Additionally, they may undergo extensive testing for toxicity and pharmacokinetics to determine their suitability for further development as drugs. The compound's role in research may also involve its use as a tool in biochemical assays or as a lead compound for drug discovery. For precise details regarding its characteristics, including its specific molecular structure and biological activity, consulting specialized databases or scientific literature is recommended.

<p>BRD-K20733377 is a Bcl-2 inhibitor that exhibits selective cytotoxicity toward senescent cells, specifically inhibiting the activity of etoposide-induced senescent IMR-90 cells with an IC50 of 10.7 μM. Additionally, BRD-K20733377 reduces the mRNA expression of aging-related genes p16, p21, and KI67 in aged mouse models.</p>

CAS 452350-43-5

BRD-K20733377

BRD-K20733377

Ref: TM-T201286