CAS 4537-76-2

Distearoylphosphatidylethanolamine

Description:

Distearoylphosphatidylethanolamine (DSPE) is a phospholipid characterized by its two stearic acid (C18) fatty acid chains attached to a glycerol backbone, which is further linked to a phosphoethanolamine head group. This amphiphilic molecule exhibits both hydrophilic and hydrophobic properties, making it an essential component in biological membranes and a key ingredient in drug delivery systems. DSPE is typically found in a bilayer structure, contributing to membrane fluidity and stability. It has a high melting point due to the saturated nature of its fatty acid chains, which influences its phase behavior in lipid formulations. DSPE is often utilized in the formulation of liposomes and nanoparticles for targeted drug delivery, as it can enhance the stability and circulation time of therapeutic agents in the bloodstream. Additionally, its ability to form stable lipid bilayers makes it valuable in various biotechnological applications, including vaccine development and gene delivery systems. Overall, DSPE is a versatile compound with significant implications in pharmaceutical and biomedical research.

Formula: C₄₁H₈₂NO₈P

InChI: InChI=1S/C41H82NO8P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(43)47-37-39(38-49-51(45,46)48-36-35-42)50-41(44)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h39H,3-38,42H2,1-2H3,(H,45,46)

InChI key: InChIKey=LVNGJLRDBYCPGB-UHFFFAOYSA-N

SMILES: C(OC(CCCCCCCCCCCCCCCCC)=O)(COC(CCCCCCCCCCCCCCCCC)=O)COP(OCCN)(=O)O

Synonyms:

• Stearin, 1,2-di-, dihydrogen phosphate, 2-aminoethyl ester
• Stearin, 1,2-di-, phosphate, 2-aminoethyl ester
• Octadecanoic acid, 1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
• Stearin, 1,2-di-, 2-aminoethyl hydrogen phosphate
• Octadecanoic acid, 1,1′-[1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester
• 1,2-distearoylphosphatidylethanolamine
• 1-((((2-Aminoethoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl octadecanoate
• Dc18pe
• 3-[[(2-Aminoethoxy)(hydroxy)phosphoryl]oxy]propane-1,2-diyl Distearate
• Distearoly-L-phosphatidylethanolamine

1,2-Distearoyl-rac-glycero-3-phosphoethanolamine

CAS: 4537-76-2

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Formula: C₄₁H₈₂NO₈P

Purity: Min. 95%

Molecular weight: 748.07 g/mol

Ref: 3D-FD172109

1,2-Distearoyl-rac-glycero-3-phosphoethanolamine

CAS: 4537-76-2

1,2-Distearoyl-rac-glycero-3-phosphoethanolamine (DSPE) is a phospholipid that has been widely used in various research applications. It has shown promising results in myocardial studies, where it was found to have pressor effects on cardiac cells. DSPE is also known for its role in fatty acid metabolism and has been used in sequence analysis of fatty acids. In addition, DSPE is commonly used as a research chemical for studying autophagy and its regulatory mechanisms. It has also shown potential in the treatment of uveitis, a condition affecting the eye, due to its specific localization properties. DSPE has been extensively studied in human cells and has been found to be safe for use in research settings. Its unique characteristics make it a valuable tool for researchers working in various fields such as cardiology, biochemistry, and molecular biology.

Formula: C₄₁H₈₂NO₈P

Purity: Min. 95 Area-%

Molecular weight: 748.09 g/mol

Ref: 3D-D-7860