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CAS 4537-78-4

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Distearoylphosphatidylglycerol

Description:
Distearoylphosphatidylglycerol (DSPG) is a phospholipid characterized by its two stearic acid chains attached to a glycerol backbone, making it a member of the glycerophospholipid family. It has a hydrophilic head group consisting of a phosphate and glycerol moiety, which contributes to its amphiphilic nature, allowing it to form bilayers in aqueous environments. DSPG is commonly used in biochemistry and pharmaceutical applications, particularly in the formulation of liposomes and drug delivery systems due to its ability to encapsulate hydrophobic compounds. Its structural properties enable it to participate in membrane fusion and stabilization processes. Additionally, DSPG can influence membrane fluidity and permeability, making it a valuable component in studies related to cell membranes and lipid interactions. The substance is typically found in a solid state at room temperature and is soluble in organic solvents. Its unique characteristics make it an important subject of research in fields such as membrane biology, nanotechnology, and drug formulation.
Formula:C42H83O10P
InChI:InChI=1S/C42H83O10P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-37-40(38-51-53(47,48)50-36-39(44)35-43)52-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h39-40,43-44H,3-38H2,1-2H3,(H,47,48)
InChI key:InChIKey=FVJZSBGHRPJMMA-UHFFFAOYSA-N
SMILES:C(COP(OCC(CO)O)(=O)O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O
Synonyms:
  • Stearin, 1,2-di-, 1-glycerophosphate
  • Octadecanoic acid, 1,1′-[1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester
  • Distearoylphosphatidylglycerol
  • Stearic acid, 3-hydroxypropylene ester hydrogen 2,3-dihydroxypropyl phosphate
  • Octadecanoic acid, 1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
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Found 2 products.
  • Distearoyl phosphatidylglycerol
    TLC
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    Distearoyl phosphatidylglycerol

    CAS:
    Formula:C42H83O10P
    Molecular weight:779.09

    Ref: 4Z-C-5919

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  • 1,2-Distearoyl-sn-glycero-3-phosphorylglycerol
    TRC
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    1,2-Distearoyl-sn-glycero-3-phosphorylglycerol

    Controlled Product
    CAS:
    <p>Applications 1,2-Distearoyl-sn-glycero-3-phosphorylglycerol is used as a component of a loposomal delivery system that coordinates the release of irinotecan and floxuridine in vivo. It is also used to encapsulate anthracyclines and deliver them to tumors.<br>References Tardi, P., et al.: Biochimica et Biophysica Acta, Biomembranes, 1768, 678 (2007); Gabizon, A., et al.: J. Drug Targeting, 3, 391 (1996)<br></p>
    Formula:C42H83O10P
    Color and Shape:Neat
    Molecular weight:779.076

    Ref: TR-D479240

    10mg
    282.00€
    100mg
    1,905.00€