CAS 454-16-0

2-Fluoro-5-nitroanisole

Description:

2-Fluoro-5-nitroanisole is an organic compound characterized by the presence of a fluorine atom, a nitro group, and a methoxy group attached to a benzene ring. Its molecular structure features a fluorine atom at the 2-position and a nitro group at the 5-position relative to the methoxy group, which is located at the 1-position of the aromatic ring. This compound is typically a pale yellow solid and is known for its moderate solubility in organic solvents. It exhibits properties typical of nitro-substituted aromatic compounds, including potential reactivity in electrophilic substitution reactions. The presence of both the nitro and fluoro groups can influence its electronic properties, making it a useful intermediate in organic synthesis and pharmaceuticals. Additionally, 2-fluoro-5-nitroanisole may exhibit biological activity, which can be of interest in medicinal chemistry. Safety data should be consulted for handling and storage, as with many nitro compounds, it may pose health and environmental risks.

Formula: C₇H₆FNO₃

InChI: InChI=1/C7H6FNO3/c1-12-7-4-5(9(10)11)2-3-6(7)8/h2-4H,1H3

SMILES: COc1cc(ccc1F)N(=O)=O

Synonyms:

• 2-Fluoro-5-nitrophenyl methyl ether
• 4-Fluoro-3-methoxynitrobenzene
• Benzene, 1-fluoro-2-methoxy-4-nitro-
• 1-Fluoro-2-Methoxy-4-Nitrobenzene

1-Fluoro-2-methoxy-4-nitrobenzene

CAS: 454-16-0

Formula: C₇H₆FNO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 171.1258

Ref: IN-DA0037TN

2-Fluoro-5-nitroanisole

CAS: 454-16-0

2-Fluoro-5-nitroanisole

Formula: C₇H₆FNO₃

Purity: ≥95%

Color and Shape: light yellow/orange solid

Molecular weight: 171.13g/mol

Ref: 54-PC4443

2-Fluoro-5-nitroanisole

CAS: 454-16-0

2-Fluoro-5-nitroanisole is a prophylactic agent that has been shown to be effective in protecting Rhesus monkeys against malaria. It is also an analog of chloroquine, which has been used as a prophylactic agent against malaria. 2-Fluoro-5-nitroanisole prevents the development of malaria by interfering with the growth and reproduction of plasmodium. The mechanism may be due to its ability to inhibit the synthesis of DNA, RNA and protein in the parasite's host cell, leading to schizonticidal activity and death.

Formula: C₇H₆FNO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 171.13 g/mol

Ref: 3D-FF33946

4-Fluoro-3-methoxynitrobenzene

CAS: 454-16-0

Formula: C₇H₆FNO₃

Purity: 97%

Color and Shape: Yellow powder

Molecular weight: 171.127

Ref: 10-F045066

2-Fluoro-5-nitroanisole

Controlled Product

CAS: 454-16-0

Applications 2-Fluoro-5-nitroanisole

Formula: C₇H₆FNO₃

Color and Shape: Neat

Molecular weight: 171.13

Ref: TR-F597580