CAS 4547-02-8

7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione

Description:

7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione, with the CAS number 4547-02-8, is a member of the benzodiazepine class of compounds, which are known for their psychoactive properties. This compound features a benzodiazepine core structure, characterized by a fused benzene and diazepine ring, with a chlorine substituent at the 7-position and a phenyl group at the 5-position. The presence of a thione functional group at the 2-position contributes to its unique chemical reactivity and potential biological activity. Typically, benzodiazepines exhibit sedative, anxiolytic, and muscle relaxant effects, and the specific substitution pattern of this compound may influence its pharmacological profile. The compound is likely to be a solid at room temperature and may have moderate solubility in organic solvents. Its synthesis and characterization would involve standard organic chemistry techniques, and it may be of interest in medicinal chemistry for the development of new therapeutic agents. Safety and handling precautions should be observed due to the potential biological effects associated with benzodiazepines.

Formula: C₁₅H₁₁ClN₂S

InChI: InChI=1S/C15H11ClN2S/c16-11-6-7-13-12(8-11)15(17-9-14(19)18-13)10-4-2-1-3-5-10/h1-8H,9H2,(H,18,19)

InChI key: InChIKey=ULILTJWAJZIROM-UHFFFAOYSA-N

SMILES: ClC=1C=C2C(=NCC(=S)NC2=CC1)C3=CC=CC=C3

Synonyms:

• 1,3-Dihydro-7-chloro-5-phenyl-2H-1,4-benzodiazepine-2-thione
• 2H-1,4-benzodiazepine-2-thione, 7-chloro-1,3-dihydro-5-phenyl-
• 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione
• Benzp-Dinitride-Thio-Ketone
• Demethylsulazepam

7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione

Controlled Product

CAS: 4547-02-8

Applications 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione (cas# 4547-02-8) is a positive allosteric modulator for the muscarinic M1 receptor, which could be a potential treament for the Alzheimer's disease or Schizophrenia.
References Flohr, A., et al.: Bioorg. Med. Chem. Lett., 27, 5415 (2017)

Formula: C₁₅H₁₁ClN₂S

Color and Shape: Beige

Molecular weight: 286.7792

Ref: TR-C365295

7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione

Controlled Product

CAS: 4547-02-8

7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione is a reagent that is used as a starting material for the synthesis of various organic compounds. It can be used in the production of pharmaceuticals, pesticides and other chemicals. 7CBDT has been found to be a useful scaffold for complex compounds and as a building block for fine chemicals.

Formula: C₁₅H₁₁ClN₂S

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 286.78 g/mol

Ref: 3D-FC19967

7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione (1 mg/ml in Acetonitrile)

Controlled Product

CAS: 4547-02-8

Formula: C₁₅H₁₁ClN₂S

Color and Shape: Single Solution

Molecular weight: 286.7792

Ref: TR-KIT3590

Thionordazepam

CAS: 4547-02-8

Formula: C₁₅H₁₁ClN₂S

Molecular weight: 286.8

Ref: ST-EA-CP-A14022