CAS 4548-34-9

Tranylcypromine (2-PCPA) HCl

CAS: 4548-34-9

Formula: C₉H₁₂ClN

Purity: 97%

Color and Shape: Solid

Molecular weight: 169.6513

Ref: IN-DA00DJQF

(+)-Tranylcypromine HCl ((+)-trans-2-Phenylcyclopropylamine HCl)

CAS: 4548-34-9

Formula: C₉H₁₁N·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 133.19 36.46

Ref: 4Z-T-676

(1S,2R)-2-Phenylcyclopropan-1-amine hydrochloride

CAS: 4548-34-9

(1S,2R)-2-Phenylcyclopropan-1-amine hydrochloride

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 169.65g/mol

Ref: 54-OR310537

Tranylcypromine Hydrochloride

Controlled Product

CAS: 4548-34-9

Applications Tranylcypromine is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively.
References Zhang, W., et al.: Drug Metab. Dispos., 29, 897 (2001); Hong S., et al.: J. Biol. Chem., 255, 9538 (1980); Taavitsainen, P., et al.: Drug Metab. Dispos., 29, 217 (2001); Negishi, T., et al.: Environ. Health Perspect., 112, 1159 (2004)

Formula: C₉H₁₂ClN

Color and Shape: Neat

Molecular weight: 169.65

Ref: TR-T715000

(1S,2R)-Tranylcypromine-d5 Hydrochloride

Controlled Product

CAS: 4548-34-9

Formula: C₉H₆D₅N•HCl

Color and Shape: Neat

Molecular weight: 138.12 + (36.46)

Ref: TR-T715002

Tranylcypromine Hydrochloride (1 mg/mL in Methanol)

Controlled Product

CAS: 4548-34-9

Formula: C₉H₁₂ClN

Color and Shape: Single Solution

Molecular weight: 169.65

Ref: TR-KIT8185

(+)-Tranylcypromine hydrochloride

Controlled Product

CAS: 4548-34-9

(+)-Tranylcypromine hydrochloride is a drug that is used for the treatment of depression. It inhibits monoamine oxidase (MAO) and reversibly inhibits the activity of tyrosine hydroxylase, which are enzymes involved in the production of amines. The binding of this drug to lysine residues on the enzyme MAO-A prevents the oxidation of dopamine and other neurotransmitters, such as serotonin. This drug has shown to have pluripotent effects in animal studies. (+)-Tranylcypromine hydrochloride has been shown to induce dedifferentiation in human liver cells grown in culture, which may be due to its ability to inhibit protein synthesis. There are many known drug interactions with (+)-tranylcypromine hydrochloride. Clinical studies have found that it increases cardiovascular toxicity when taken with drugs such as beta blockers, calcium channel blockers, and clonidine.

Formula: C₉H₁₁N·HCl

Purity: Min. 95%

Molecular weight: 169.65 g/mol

Ref: 3D-EAA54834

(1S,2R)-Tranylcypromine hydrochloride

CAS: 4548-34-9

(1S,2R)-Tranylcypromine hydrochloride ((1S,2R)-SKF 385), a potent antidepressant, functions by inhibiting both MAO and LSD1.

Formula: C₉H₁₂ClN

Color and Shape: Solid

Molecular weight: 169.651

Ref: TM-T71826