CAS 455-16-3

4-Methylbenzenesulfonyl fluoride

Description:

4-Methylbenzenesulfonyl fluoride, also known as p-toluenesulfonyl fluoride (TsF), is an organic compound characterized by a sulfonyl fluoride functional group attached to a methyl-substituted benzene ring. It is a colorless to pale yellow liquid with a pungent odor and is soluble in organic solvents such as acetone and dichloromethane, but has limited solubility in water. This compound is notable for its reactivity, particularly as a sulfonylating agent in organic synthesis, where it can be used to introduce sulfonyl groups into various substrates. It is also employed as a reagent in the preparation of sulfonamides and in the modification of proteins and peptides. Due to the presence of the sulfonyl fluoride group, it can act as an electrophile, making it useful in nucleophilic substitution reactions. However, it is important to handle this compound with care, as it can be hazardous, exhibiting irritant properties and potential toxicity. Proper safety measures should be taken when working with 4-Methylbenzenesulfonyl fluoride in a laboratory setting.

Formula: C₇H₇FO₂S

InChI: InChI=1S/C7H7FO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3

InChI key: InChIKey=IZZYABADQVQHLC-UHFFFAOYSA-N

SMILES: S(F)(=O)(=O)C1=CC=C(C)C=C1

Synonyms:

• 1-(Fluorosulfonyl)-4-methylbenzene
• 4-Methylbenzenesulfonyl fluoride
• 4-Methylphenylsulfonyl fluoride
• 4-Tolylsulfonyl fluoride
• Benzenesulfonyl fluoride, 4-methyl-
• NSC 2749
• Para-Toluenesulfonyl Fluoride
• Toluene-4-sulfonyl fluoride
• Tosyl fluoride
• p-Methylbenzenesulfonyl fluoride
• p-Methylphenylsulfonyl fluoride
• p-Tolylsulfonyl fluoride

4-Methylbenzenesulfonyl Fluoride

CAS: 455-16-3

Formula: C₇H₇FO₂S

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 174.19

Ref: 3B-M3518

p-Toluenesulfonyl fluoride, 98%

CAS: 455-16-3

p-Toluenesulfonyl fluoride is used for sulfonylation of organometallic reagents as a simple, one-step synthesis of sulfones. It is useful in the treatment of Alzheimer?s disease. It is used to study the DNS polymerase from spinach leaf extracts. It was used in isolation and separation of Pseudomona

Formula: C₇H₇FO₂S

Purity: 98%

Color and Shape: White to cream to yellow, Crystals or powder or crystalline powder or lumps

Molecular weight: 174.19

Ref: 02-L12204

p-Toluenesulfonyl fluoride

CAS: 455-16-3

Formula: C₇H₇FO₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 174.1927

Ref: IN-DA003U14

Toluene-4-sulphonyl fluoride

CAS: 455-16-3

Toluene-4-sulphonyl fluoride

Purity: 98%

Color and Shape: White Solid

Molecular weight: 174.19g/mol

Ref: 54-PC6991

4-Toluenesulfonyl fluoride

CAS: 455-16-3

Formula: C₇H₇FO₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 174.19

Ref: 10-F002463

4-Toluensulfonyl fluoride

CAS: 455-16-3

4-Toluensulfonyl fluoride is an organic compound that is used as a reagent in organic synthesis. It can be used as a building block for the synthesis of other compounds, such as pharmaceuticals, agrochemicals and dyes. The chemical formula for 4-toluensulfonyl fluoride is C6H5SO2F. It has a molecular weight of 155.07 g/mol and boiling point of 183 °C at 760 mmHg pressure.

Formula: C₁₂H₁₂O₃

Molecular weight: 204.22 g/mol

Ref: 3D-J-640211

4-Toluensulfonyl fluoride

CAS: 455-16-3

4-Toluensulfonyl fluoride is a cell lysis agent that disrupts the disulfide bonds in proteins by reacting with them. It can be used in vitro to study mechanisms of protein synthesis and has been shown to have inhibitory properties towards polymerase chain reactions. 4-Toluensulfonyl fluoride has also been shown to have antimicrobial effects against bacteria in vivo, which may be due to its ability to bind to the polymerase chain reaction enzyme and inhibit its activity. 4-Toluensulfonyl fluoride has been found to have proteolytic, enzyme-inhibiting, and transcriptional regulatory properties.

Purity: Min. 95%

Ref: 3D-FT172325