CAS 455-24-3

4-(Trifluoromethyl)benzoic acid

Description:

4-(Trifluoromethyl)benzoic acid, with the CAS number 455-24-3, is an aromatic carboxylic acid characterized by the presence of a trifluoromethyl group (-CF3) attached to the para position of a benzoic acid structure. This compound typically appears as a white crystalline solid and is known for its high thermal stability and relatively low solubility in water, while being more soluble in organic solvents. The trifluoromethyl group imparts unique electronic properties, enhancing the acidity of the carboxylic acid functional group and influencing its reactivity in various chemical reactions. It is often utilized in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals, due to its ability to modulate biological activity. Additionally, 4-(Trifluoromethyl)benzoic acid can serve as a building block in the synthesis of more complex fluorinated compounds, making it valuable in materials science and medicinal chemistry. Safety precautions should be observed when handling this compound, as with many fluorinated substances, due to potential toxicity and environmental concerns.

Formula: C₈H₅F₃O₂

InChI: InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-5(2-4-6)7(12)13/h1-4H,(H,12,13)

InChI key: InChIKey=SWKPKONEIZGROQ-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C1=CC=C(C(O)=O)C=C1

Synonyms:

• 4-(Trifluoromethyl)Cyclohexanecarboxylate
• 4-(Trifluoromethyl)benzoic acid
• 4-Carboxybenzotrifluoride
• 4-Trifluoromethylbenzoic acid
• Benzoic acid, 4-(trifluoromethyl)-
• C 71640
• Difluoromethylbenzene
• NSC 88327
• p-(Trifluoromethyl)benzoic acid
• p-Toluic acid, α,α,α-trifluoro-
• p-Trifluoromethylbenzoic acid

4-(Trifluoromethyl)benzoic Acid

CAS: 455-24-3

Formula: C₈H₅F₃O₂

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 190.12

Ref: 3B-T1145

4-(Trifluoromethyl)benzoic acid, 98+%

CAS: 455-24-3

4-(Trifluoromethyl)benzoic acid was used in the synthesis of salicylanilide 4-(trifluoromethyl)benzoates via N,N?-dicyclohexylcarbodiimide coupling in dry N,N-dimethylformamide. It was used as internal standard during the ultra trace analysis of fluorinated aromatic carboxylic acids by GC/MS method.

Formula: C₈H₅F₃O₂

Purity: 98+%

Color and Shape: White, Powder or lumps

Molecular weight: 190.12

Ref: 02-A14494

4-(Trifluoromethyl)benzoic acid

CAS: 455-24-3

Formula: C₈H₅F₃O₂

Purity: 98%

Color and Shape: Crystalline Powder,Lumps

Molecular weight: 190.121

Ref: 10-F002701

4-(Trifluoromethyl)Benzoic Acid

CAS: 455-24-3

Formula: C₈H₅F₃O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 190.1193

Ref: IN-DA003KBN

4-(Trifluoromethyl)benzoic acid

CAS: 455-24-3

4-(Trifluoromethyl)benzoic acid

Formula: C₈H₅F₃O₂

Purity: 98%

Color and Shape: white powder

Molecular weight: 190.1193g/mol

Ref: 54-PC7540

Fluralaner Impurity 26

CAS: 455-24-3

Formula: C₈H₅F₃O₂

Molecular weight: 190.12

Ref: 4Z-F-179036

4-(Trifluoromethyl)benzoic Acid

CAS: 455-24-3

Formula: C₈H₅F₃O₂

Molecular weight: 190.12

Ref: ST-EA-CP-F8025