CAS 456-41-7

3-Fluorobenzyl bromide

Description:

3-Fluorobenzyl bromide, with the CAS number 456-41-7, is an organic compound characterized by the presence of a fluorine atom and a bromine atom attached to a benzyl group. It features a benzene ring substituted at the meta position with a fluorine atom and a bromomethyl group (-CH2Br). This compound is typically a colorless to pale yellow liquid with a distinctive aromatic odor. It is known for its reactivity, particularly in nucleophilic substitution reactions, where the bromine atom can be replaced by various nucleophiles. The presence of the fluorine atom can influence the electronic properties of the molecule, enhancing its reactivity and making it useful in various synthetic applications, including the preparation of pharmaceuticals and agrochemicals. Additionally, 3-fluorobenzyl bromide is considered a valuable intermediate in organic synthesis due to its ability to participate in cross-coupling reactions. As with many halogenated compounds, it should be handled with care due to potential toxicity and environmental concerns.

Formula: C₇H₆BrF

InChI: InChI=1/C7H6BrF/c8-5-6-2-1-3-7(9)4-6/h1-4H,5H2

InChI key: InChIKey=SCBZBMXPJYMXRC-UHFFFAOYSA-N

SMILES: C(Br)C1=CC(F)=CC=C1

Synonyms:

• (3-Fluorophenyl)methyl bromide
• 1-(Bromomethyl)-3-Fluorobenzene
• 1-(Chloromethyl)-3-Fluorobenzene
• 1-Fluoro-3-(bromomethyl)benzene
• 3-(Bromomethyl)fluorobenzene
• 3-Fluoro(Bromomethyl)Benzene
• Benzene, 1-(bromomethyl)-3-fluoro-
• NSC 91494
• Toluene, α-bromo-m-fluoro-
• alpha-Bromo-3-fluorotoluene
• m-Fluorobenzyl bromide
• α-Bromo-3-fluorotoluene
• 3-Fluorobenzyl bromide
• 1-(bromomethyl)-3-fluoro-benzen
• 3-Fluorobenzylbromide,98%
• 3-FLUOROBENZYL BROMIDE 97% (GC)
• Toluene, alpha-bromo-m-fluoro-
• ALPHA-BROMO-M-FLUOROTOLUENE
• 3-Fluorobenzyl bromide 98%

3-Fluorobenzyl Bromide

CAS: 456-41-7

Formula: C₇H₆BrF

Purity: >97.0%(GC)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 189.03

Ref: 3B-F0208

3-Fluorobenzyl bromide, 95%

CAS: 456-41-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₆BrF

Purity: 95%

Color and Shape: Clear colorless to yellow, Liquid

Molecular weight: 189.03

Ref: 02-A15446

1-(bromomethyl)-3-fluorobenzene

CAS: 456-41-7

Formula: C₇H₆BrF

Purity: 98%

Color and Shape: Liquid

Molecular weight: 189.0249

Ref: IN-DA0033PL

3-Fluorobenzyl bromide

CAS: 456-41-7

3-Fluorobenzyl bromide

Formula: C₇H₆BrF

Purity: 96%

Color and Shape: yellow liquid

Molecular weight: 189.02g/mol

Ref: 54-PC3694

3-Fluorobenzyl bromide

CAS: 456-41-7

Formula: C₇H₆BrF

Purity: 99.0%

Color and Shape: Liquid, Clear Liquid

Molecular weight: 189.027

Ref: 10-F002171

3-Fluorobenzyl Bromide

Controlled Product

CAS: 456-41-7

Applications 3-Fluorobenzyl Bromide is a substituted benzyl bromide used as a reagent in the preparation of wide range of biologically active compounds such as antidiabetic drugs, anti-virals and anti-cancer agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhang, Y. et al.: Eur. J. Med. Chem., 53, 356 (2012); Wang, L.-J. et al.: Bioorg. Med. Chem. Lett., 22, 3473 (2012);

Formula: C₇H₆BrF

Color and Shape: Neat

Molecular weight: 189.02

Ref: TR-F588605

3-Fluorobenzyl bromide

CAS: 456-41-7

3-Fluorobenzyl bromide is a fluorinated benzyl derivative that can be used as a fluorescent probe for the study of cellular uptake and metabolism. 3-Fluorobenzyl bromide has been shown to have potent inhibitory activity against the growth of cancer cells in culture. It has also been shown to reduce ischemia reperfusion injury in cardiac tissue. The pharmacokinetic properties of 3-fluorobenzyl bromide have been studied in detail, revealing a rapid uptake into cells and elimination by renal excretion. This compound also inhibits the growth of P. aeruginosa in an animal model, with no effect on other bacterial strains or mammalian cells.

Purity: Min. 95%

Ref: 3D-FF38630