CAS 456-56-4

[(Trifluoromethyl)thio]benzene

Description:

[(Trifluoromethyl)thio]benzene, also known as trifluoromethylthiobenzene, is an aromatic compound characterized by the presence of a trifluoromethyl group (-CF3) and a thiol group (-S-) attached to a benzene ring. This compound is notable for its unique electronic properties, which arise from the strong electron-withdrawing nature of the trifluoromethyl group. As a result, [(Trifluoromethyl)thio]benzene exhibits increased reactivity in electrophilic aromatic substitution reactions compared to unsubstituted benzene derivatives. It is typically a colorless to pale yellow liquid with a distinct odor, and it is relatively stable under standard conditions. The presence of the sulfur atom contributes to its potential applications in organic synthesis and materials science, particularly in the development of novel pharmaceuticals and agrochemicals. Additionally, due to the trifluoromethyl group, this compound may exhibit unique solubility and volatility characteristics, making it of interest in various chemical processes and applications. Safety precautions should be observed when handling this compound, as it may pose health risks.

Formula: C₇H₅F₃S

InChI: InChI=1S/C7H5F3S/c8-7(9,10)11-6-4-2-1-3-5-6/h1-5H

InChI key: InChIKey=YQQKTCBMKQQOSM-UHFFFAOYSA-N

SMILES: S(C(F)(F)F)C1=CC=CC=C1

Synonyms:

• (Trifluoromethylthio)benzene
• Benzene, [(trifluoromethyl)thio]-
• Phenyl trifluoromethyl sulphide
• Phenyl trifluoromethyl thioether
• Sulfide, phenyl trifluoromethyl
• Trifluoromethyl phenyl sulphide
• Trifluoromethyl phenyl thioether
• Trifluoromethylthiobenzene
• [(Trifluoromethyl)Sulfanyl]Benzene
• [(Trifluoromethyl)thio]benzene
• alpha,alpha,alpha-Trifluorothioanisole

Phenyl Trifluoromethyl Sulfide

CAS: 456-56-4

Formula: C₇H₅F₃S

Purity: >97.0%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 178.17

Ref: 3B-P1693

Phenyl trifluoromethyl sulfide, 98%

CAS: 456-56-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₅F₃S

Purity: 98%

Color and Shape: Liquid, Clear colorless to pale yellow

Molecular weight: 178.17

Ref: 02-L10114

Trifluoromethylthiobenzene

CAS: 456-56-4

Formula: C₇H₅F₃S

Purity: 97%

Color and Shape: Liquid

Molecular weight: 178.1748

Ref: IN-DA0035QZ

Phenyl trifluoromethyl sulphide

CAS: 456-56-4

Phenyl trifluoromethyl sulphide

Formula: C₇H₅F₃S

Purity: 98%

Color and Shape: clear. colourless liquid

Molecular weight: 178.17g/mol

Ref: 54-PC6229

Phenyl trifluoromethyl sulfide

CAS: 456-56-4

Formula: C₇H₅F₃S

Purity: 98%

Color and Shape: Liquid, Clear

Molecular weight: 178.17

Ref: 10-F001525

Phenyl trifluoromethylsulfide

CAS: 456-56-4

Phenyl trifluoromethylsulfide is a diazonium salt that reacts with serine proteases to form reactive functional groups, resulting in the formation of reaction products. The chlorine atom in phenyl trifluoromethylsulfide reacts with hydroxide ions, forming a chloroformate anion. This anion then reacts with nucleophilic amino acids such as lysine and arginine in the protease. This nucleophilic attack induces inflammation in inflammatory diseases such as asthma and arthritis. Phenyl trifluoromethylsulfide has been shown to be effective against ns3 protease found in plasma mass spectrometry samples of patients with chronic respiratory disease (COPD).

Formula: C₇H₅F₃S

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 178.18 g/mol

Ref: 3D-FP10595