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CAS 4564-87-8

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Carbomycin

Description:
Carbomycin is a naturally occurring antibiotic that belongs to the macrolide class of compounds. It is primarily produced by the fermentation of certain strains of the bacterium *Streptomyces griseus*. The chemical structure of carbomycin features a large lactone ring, which is characteristic of macrolides, and it possesses a unique sugar moiety that contributes to its biological activity. This antibiotic exhibits potent antibacterial properties, particularly against Gram-positive bacteria, making it useful in treating various infections. Carbomycin works by inhibiting bacterial protein synthesis, thereby preventing the growth and reproduction of susceptible bacteria. Its effectiveness and mechanism of action are similar to other macrolides, such as erythromycin, but it has distinct pharmacological properties. Due to its specific activity and the emergence of antibiotic resistance, carbomycin is of interest in both clinical and research settings, particularly in the development of new antimicrobial agents. However, its use may be limited by factors such as toxicity and the availability of alternative antibiotics.
Formula:C42H67NO16
InChI:InChI=1S/C42H67NO16/c1-21(2)16-32(47)57-40-25(6)53-34(20-42(40,8)50)58-37-24(5)54-41(36(49)35(37)43(9)10)59-38-27(14-15-44)17-22(3)28(46)12-13-29-30(56-29)18-23(4)52-33(48)19-31(39(38)51-11)55-26(7)45/h12-13,15,21-25,27,29-31,34-41,49-50H,14,16-20H2,1-11H3/b13-12+/t22-,23-,24-,25+,27+,29+,30+,31?,34+,35-,36-,37-,38+,39+,40+,41+,42-/m1/s1
InChI key:InChIKey=FQVHOULQCKDUCY-FSTLRIQASA-N
SMILES:O([C@@H]1[C@@H](OC)C(OC(C)=O)CC(=O)O[C@H](C)C[C@]2([C@](\C=C\C(=O)[C@H](C)C[C@@H]1CC=O)(O2)[H])[H])[C@H]3[C@H](O)[C@@H](N(C)C)[C@H](O[C@H]4C[C@@](C)(O)[C@@H](OC(CC(C)C)=O)[C@H](C)O4)[C@@H](C)O3
Synonyms:
  • 4,17-Dioxabicyclo[14.1.0]heptadecane, leucomycin V deriv.
  • 6-{[6-{[(1S,3R,7R,8S,9S,10R,12R,14E)-7-(acetyloxy)-8-methoxy-3,12-dimethyl-5,13-dioxo-10-(2-oxoethyl)-4,17-dioxabicyclo[14.1.0]heptadec-14-en-9-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyltetrahydro-2H-pyran-3-yl]oxy}-4-hydroxy-2,4-dimethyltetrahydro-2H-pyran-3-yl 3-methylbutanoate (non-preferred name)
  • 9-Deoxy-12,13-epoxy-9-oxoleucomycin V 3-acetate 4b-(3-methylbutanoate)
  • Carbomycin
  • Carbomycin A
  • Deltamycin A4
  • Deltamycin A<sub>4</sub>
  • Leucomycin V, 9-deoxy-12,13-epoxy-12,13-dihydro-9-oxo-, 3-acetate 4<sup>B</sup>-(3-methylbutanoate), (12S,13S)-
  • M 4209
  • Magnamycin A
  • See more synonyms
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