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CAS 458532-82-6

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2-Bromopyridine-4-boronic acid pinacol ester

Description:
2-Bromopyridine-4-boronic acid pinacol ester is an organoboron compound characterized by the presence of a bromine atom and a boronic acid moiety, which is esterified with pinacol. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its form and purity. It is soluble in organic solvents such as dichloromethane and tetrahydrofuran, but has limited solubility in water due to its hydrophobic characteristics. The presence of the bromine atom makes it a useful intermediate in various organic synthesis reactions, particularly in cross-coupling reactions like Suzuki-Miyaura coupling, where it can participate in the formation of carbon-carbon bonds. The boronic acid functionality allows for the formation of stable complexes with diols, enhancing its utility in synthetic chemistry. Additionally, this compound may exhibit moderate toxicity, necessitating appropriate safety precautions during handling and use in laboratory settings. Overall, 2-Bromopyridine-4-boronic acid pinacol ester is a valuable reagent in the field of organic synthesis and medicinal chemistry.
Formula:C11H15BBrNO2
InChI:InChI=1/C11H15BBrNO2/c1-10(2)11(3,4)16-12(15-10)8-5-6-14-9(13)7-8/h5-7H,1-4H3
SMILES:CC1(C)C(C)(C)OB(c2ccnc(c2)Br)O1
Synonyms:
  • 2-Bromo-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
  • 2-(2-Bromo-4-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 2-Bromo-4-pyridylboronic Acid Pinacol Ester
  • 2-broMo-4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine
  • 2-BROMOPYRIDINE-4-BORONIC ACID PINACOL ESTER
  • 2-Bromo-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine 97%
  • 2-BROMO-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE ISO 9001：2015 REACH
  • Pyridine, 2-bromo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
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