CAS 459-04-1

2-(4-Fluorophenyl)acetyl chloride

Description:

2-(4-Fluorophenyl)acetyl chloride, with the CAS number 459-04-1, is an organic compound characterized by the presence of an acetyl chloride functional group attached to a 4-fluorophenyl moiety. This compound typically appears as a colorless to pale yellow liquid and is known for its reactivity, particularly in acylation reactions. It is a derivative of acetyl chloride, where the acetyl group is substituted with a 4-fluorophenyl group, enhancing its electrophilic character. The presence of the fluorine atom can influence the compound's physical and chemical properties, such as its boiling point and solubility. 2-(4-Fluorophenyl)acetyl chloride is often used in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals, due to its ability to introduce the acetyl group into various substrates. However, it should be handled with care, as it is corrosive and can release hydrochloric acid upon hydrolysis. Proper safety precautions, including the use of personal protective equipment, are essential when working with this compound.

Formula: C₈H₆ClFO

InChI: InChI=1S/C8H6ClFO/c9-8(11)5-6-1-3-7(10)4-2-6/h1-4H,5H2

InChI key: InChIKey=SIOJFYRPBYGHOO-UHFFFAOYSA-N

SMILES: C(C(Cl)=O)C1=CC=C(F)C=C1

Synonyms:

• Benzeneacetyl chloride, 4-fluoro-
• 4-Fluorobenzeneacetyl chloride
• 4-Fluorophenylacetyl chloride
• (p-Fluorophenyl)acetyl chloride
• Acetyl chloride, (p-fluorophenyl)-

4-Fluorophenylacetyl chloride

CAS: 459-04-1

Formula: C₈H₆ClFO

Purity: 98%

Color and Shape: Liquid

Molecular weight: 172.5840

Ref: IN-DA003LG3

4-Fluorophenylacetyl chloride

CAS: 459-04-1

4-Fluorophenylacetyl chloride

Formula: C₈H₆ClFO

Purity: ≥95%

Color and Shape: clear. dark yellow/orange liquid

Molecular weight: 172.58404g/mol

Ref: 54-PC9663

4-Fluorophenylacetyl chloride

CAS: 459-04-1

Formula: C₈H₆ClFO

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 172.58

Ref: 10-F009229