CAS 459-86-9

Methylglyoxal bis(guanylhydrazone)

Description:

Methylglyoxal bis(guanylhydrazone), with the CAS number 459-86-9, is a chemical compound that belongs to the class of hydrazones. It is characterized by its structure, which features two guanylhydrazone groups linked to a methylglyoxal moiety. This compound is known for its potential biological activity, particularly in the context of its role as an antitumor agent and its ability to interact with various biological targets. Methylglyoxal bis(guanylhydrazone) exhibits solubility in polar solvents, which is typical for many hydrazones, and it may undergo tautomerization due to the presence of functional groups that can participate in hydrogen bonding. The compound has been studied for its effects on cellular processes, including apoptosis and cell proliferation, making it of interest in medicinal chemistry and pharmacology. However, like many chemical substances, it should be handled with care, as it may pose health risks if not managed properly.

Formula: C₅H₁₂N₈

InChI: InChI=1S/C5H12N8/c1-3(11-13-5(8)9)2-10-12-4(6)7/h2H,1H3,(H4,6,7,12)(H4,8,9,13)

InChI key: InChIKey=MXWHMTNPTTVWDM-UHFFFAOYSA-N

SMILES: C(=NNC(=N)N)(C=NNC(=N)N)C

Synonyms:

• 1,1'-((Methylethanediylidene)dinitrilo)diguanidine
• 2,2′-(1-Methyl-1,2-ethanediylidene)bis[hydrazinecarboximidamide]
• Ai3-60317
• Brn 1912590
• Guanidine, 1,1'-((methylethanediylidene)dinitrilo)di-
• Hydrazinecarboximidamide, 2,2'-(1-methyl-1,2-ethanediylidene)bis- (9CI)
• Hydrazinecarboximidamide, 2,2′-(1-methyl-1,2-ethanediylidene)bis-
• Me-GAG
• Methyl-G
• Methyl-Gag
• Methylglyoxal bis(amidinohydrazone)
• Methylglyoxal bis(guanylhydrazone)
• Mitoguanazone
• Mitoguazona
• Mitoguazona [INN-Spanish]
• Mitoguazone [INN:DCF]
• Mitoguazonum
• Mitoguazonum [INN-Latin]
• N''-{(1E,2E)-2-[(diaminomethylidene)hydrazono]-1-methylethylidene}carbonohydrazonic diamide (non-preferred name)
• NSC 32946
• Pyruvaldehyde bis(amidinohydrazone)
• Unii-Od5Q0L447W

N-{[1-(carbamimidamidoimino)propan-2-ylidene]amino}guanidine

CAS: 459-86-9

Formula: C₅H₁₂N₈

Purity: 97%

Color and Shape: Solid

Molecular weight: 184.2024

Ref: IN-DA00DDZ7

2,2'-(Propane-1,2-diylidene)bis(hydrazinecarboximidamide)

CAS: 459-86-9

2,2'-(Propane-1,2-diylidene)bis(hydrazinecarboximidamide)

Purity: 97%

Molecular weight: 184.21g/mol

Ref: 54-OR1074845

Mitoguazone

CAS: 459-86-9

Purity: 97%

Molecular weight: 184.2070007

Ref: 10-F866555

Mitoguazone

CAS: 459-86-9

Mitoguazone is an antitumor agent, blocking SAM decarboxylase, disrupting polyamine synthesis, and hindering HIV DNA integration in immune cells.

Formula: C₅H₁₂N₈

Purity: 97.47% - 98%

Color and Shape: Solid

Molecular weight: 184.2

Ref: TM-T35617