CAS 4594-45-0

6-chloro-9-(2-deoxypentofuranosyl)-9H-purine

Description:

6-Chloro-9-(2-deoxypentofuranosyl)-9H-purine, with the CAS number 4594-45-0, is a purine nucleoside analog characterized by the presence of a chlorine atom at the 6-position of the purine ring and a deoxypentofuranosyl moiety attached at the 9-position. This compound exhibits properties typical of nucleosides, including the ability to participate in biochemical processes such as nucleic acid synthesis. Its structural features suggest potential applications in medicinal chemistry, particularly in antiviral and anticancer research, as nucleoside analogs can interfere with viral replication or cellular proliferation. The presence of the chlorine substituent may enhance its biological activity or alter its pharmacokinetic properties. Additionally, the compound's solubility, stability, and reactivity can be influenced by the sugar component and the halogen substitution. Overall, 6-chloro-9-(2-deoxypentofuranosyl)-9H-purine represents a significant structure in the study of nucleoside analogs and their therapeutic potential.

Formula: C₁₀H₁₁ClN₄O₃

InChI: InChI=1/C10H11ClN4O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2

InChI key: PGEULCIODBNODW-RRKCRQDMSA-N

SMILES: C1C(C(CO)OC1n1cnc2c(Cl)ncnc12)O

Synonyms:

• 6-Chloro-9-(2'-deoxyribofuranosyl) purine
• 6-Chloropurine-2'-Deoxyriboside

6-Chloropurine 2'-deoxyriboside, 97%

CAS: 4594-45-0

6-Chloropurine 2'-deoxyriboside is used in the synthesis of 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)adenine. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The

Formula: C₁₀H₁₁ClN₄O₃

Purity: 97%

Color and Shape: White to off-white, Powder

Molecular weight: 270.67

Ref: 02-J64871

(2R,3S,5R)-5-(6-Chloro-9H-Purin-9-Yl)-2-(Hydroxymethyl)Tetrahydrofuran-3-Ol

CAS: 4594-45-0

(2R,3S,5R)-5-(6-Chloro-9H-Purin-9-Yl)-2-(Hydroxymethyl)Tetrahydrofuran-3-Ol

Formula: C₁₀H₁₁ClN₄O₃

Purity: 98%

Molecular weight: 270.676

Ref: 54-OR1026430

6-Chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine

CAS: 4594-45-0

Formula: C₁₀H₁₁ClN₄O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 270.6723

Ref: IN-DA00I8JQ

6-Chloro-9-(2''-deoxy-b-D-ribofuranosyl)purine

CAS: 4594-45-0

Formula: C₁₀H₁₁ClN₄O₃

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 270.67

Ref: 7W-GN0730

6-Chloro-9-(2'-deoxy-β-D-ribofuranosyl)purine

CAS: 4594-45-0

(2R,3S,5R)-5-(6-Chloro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol

Formula: C₁₀H₁₁ClN₄O₃

Purity: 98%

Molecular weight: 270.67

Ref: IN-DG02507996

6-Chloro-9-(2'-deoxy-β-D-ribofuranosyl)purine

CAS: 4594-45-0

6-Chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is a nucleoside analogue that inhibits the replication of the hepatitis C virus. It binds to the viral RNA polymerase and blocks the synthesis of viral RNA, thereby preventing infection. This drug also has antiviral activity against HIV and herpes simplex viruses. The antiviral effect is due to its ability to inhibit phosphatases and carboxylates, which are involved in the initiation of mRNA transcription and protein translation, respectively. 6-Chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is metabolized by deoxyadenosine kinase into 6-chloropurine ribonucleotide, which can be converted into other purines.

Formula: C₁₀H₁₁ClN₄O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 270.68 g/mol

Ref: 3D-NC06422

6-Chloropurine 2'-deoxy-β-D-ribofuranoside-13C,15N

Controlled Product

CAS: 4594-45-0

Formula: C₂C₈H₁₁Cl₁₅NN₃O₃

Color and Shape: Neat

Molecular weight: 273.651

Ref: TR-C381172