CAS 459841-96-4

Benzoic acid,4-[[[2,3-dihydro-6-[(2-methylpropyl)[(4-methyl-2-thiazolyl)sulfonyl]amino]-1H-inden-5-yl]oxy]methyl]-

Description:

Benzoic acid, 4-[[[2,3-dihydro-6-[(2-methylpropyl)[(4-methyl-2-thiazolyl)sulfonyl]amino]-1H-inden-5-yl]oxy]methyl]- is a complex organic compound characterized by its benzoic acid core, which is a carboxylic acid known for its antimicrobial properties and use as a food preservative. The structure features a substituted indene moiety, indicating potential biological activity, and a thiazole ring, which often contributes to pharmacological properties. The presence of a sulfonamide group suggests that this compound may exhibit specific interactions with biological targets, making it of interest in medicinal chemistry. Additionally, the branched alkyl group (2-methylpropyl) enhances lipophilicity, potentially influencing its solubility and permeability in biological systems. Overall, this compound's unique structural features may confer specific reactivity and biological activity, warranting further investigation for applications in pharmaceuticals or agrochemicals.

Formula: C₂₅H₂₈N₂O₅S₂

ONO-8130

CAS: 459841-96-4

ONO-8130

Purity: ≥95%

Molecular weight: 500.63g/mol

Ref: 54-BUP01102

ONO-8130

CAS: 459841-96-4

ONO-8130 is an orally available antagonist of EP1 receptor.

Formula: C₂₅H₂₈N₂O₅S₂

Purity: 97.82%

Color and Shape: Solid

Molecular weight: 500.63

Ref: TM-T21976

ONO 8130

CAS: 459841-96-4

ONO-8130 is a new, potent and selective agonist of the prostanoid receptor EP2. It has been shown to have a concentration-dependent antinociceptive effect in both anesthetized and non-anesthetized animals. In functional studies, ONO-8130 inhibits the spontaneous firing of neurons from the dorsal root ganglia (DRG) in a dose-dependent manner, which may be mediated by an action on EP2 receptors. ONO-8130 also inhibits the release of nociceptive neurotransmitters such as histamine from rat peritoneal mast cells. The drug has been found to have antihistaminic activity in rats but not in guinea pigs or mice. This may be due to its ability to activate EP2 receptors in the bladder muscle and/or its affinity for vascular endothelial cells that express EP2 receptors. These actions may account for its antihistaminic effects observed in rats but not mice or

Formula: C₂₅H₂₈N₂O₅S₂

Purity: Min. 95%

Molecular weight: 500.63 g/mol

Ref: 3D-BO178747