CAS 459844-25-8

Arylomycin B2

Description:

Arylomycin B2 is a natural product belonging to the class of cyclic peptides, specifically a member of the arylomycin family, which are known for their antibiotic properties. It is characterized by a unique structure that includes a cyclic backbone and various functional groups that contribute to its biological activity. Arylomycin B2 exhibits potent antibacterial effects, particularly against Gram-positive bacteria, by inhibiting bacterial protein synthesis. This mechanism of action is primarily due to its ability to bind to the bacterial ribosome, disrupting the translation process. The compound has garnered interest in medicinal chemistry for its potential as a lead compound in the development of new antibiotics, especially in the face of rising antibiotic resistance. Additionally, Arylomycin B2 may possess other pharmacological properties, making it a subject of ongoing research. Its stability, solubility, and bioavailability are important factors that influence its therapeutic potential and application in clinical settings.

Formula: C₄₂H₅₉N₇O₁₃

Synonyms:

• Arylomycin B2
• Alanine, N-methyl-N-(10-methyl-1-oxoundecyl)-D-seryl-D-alanylglycyl-N-methylglycyl-L-alanyl-, cyclic 42,63-(6,6'-dihydroxy-5'-nitro[1,1'-biphenyl]-3,3'-diyl) deriv.

Arylomycin B2

CAS: 459844-25-8

Arylomycin B2 is an antibiotic and a potent inhibitor of signal peptidase I (SPase I), exhibiting activity against Gram-positive bacteria.

Formula: C₄₂H₅₉N₇O₁₃

Color and Shape: Solid

Molecular weight: 869.957

Ref: TM-TN9015