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CAS 459844-30-5

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Arylomycin B7

Description:
Arylomycin B7 is a member of the arylomycin class of antibiotics, which are known for their unique mechanism of action targeting bacterial protein synthesis. This compound exhibits a broad spectrum of antibacterial activity, particularly against Gram-positive bacteria, including strains resistant to conventional antibiotics. Arylomycin B7 functions by inhibiting the bacterial signal peptidase, an enzyme crucial for the processing of secretory proteins, thereby disrupting essential cellular processes. The structure of Arylomycin B7 features a complex bicyclic core with various functional groups that contribute to its biological activity and stability. Its potential therapeutic applications are being explored, particularly in the context of rising antibiotic resistance. Additionally, Arylomycin B7 has shown promise in preclinical studies, indicating its potential as a novel antibiotic agent. However, further research is necessary to fully understand its pharmacokinetics, toxicity, and efficacy in clinical settings. Overall, Arylomycin B7 represents a significant advancement in the search for new antibiotics to combat resistant bacterial infections.
Formula:C45H65N7O13
Synonyms:
  • Alanine, N-methyl-N-(12-methyl-1-oxotetradecyl)-D-seryl-D-alanylglycyl-N-methylglycyl-L-alanyl-, cyclic 42,63-(6,6'-dihydroxy[1,1'-biphenyl]-3,3'-diyl) deriv.
  • Arylomycin B7
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  • Arylomycin B7

    CAS:
    <p>Arylomycin B7 is a lipohexapeptide antibiotic (antibiotic) that specifically targets Gram-positive bacteria.</p>
    Formula:C45H65N7O13
    Color and Shape:Solid
    Molecular weight:912.037