CAS 460746-46-7

4-[2-[2-[(2R)-2-Methyl-1-pyrrolidinyl]ethyl]-5-benzofuranyl]benzonitrile

Description:

4-[2-[2-[(2R)-2-Methyl-1-pyrrolidinyl]ethyl]-5-benzofuranyl]benzonitrile, with the CAS number 460746-46-7, is a chemical compound that belongs to a class of substances known for their potential pharmacological properties. This compound features a complex structure that includes a benzofuran moiety and a benzonitrile group, which may contribute to its biological activity. The presence of the pyrrolidine ring suggests that it may interact with various biological targets, potentially influencing neurotransmitter systems. Its molecular structure indicates that it may exhibit lipophilicity, which can affect its absorption and distribution in biological systems. Additionally, the stereochemistry of the compound, particularly the (2R) configuration, may play a crucial role in its pharmacodynamics and pharmacokinetics. Overall, while specific biological activities and therapeutic applications may require further investigation, the structural characteristics of this compound suggest it could be of interest in medicinal chemistry and drug development.

Formula: C₂₂H₂₂N₂O

InChI: InChI=1S/C22H22N2O/c1-16-3-2-11-24(16)12-10-21-14-20-13-19(8-9-22(20)25-21)18-6-4-17(15-23)5-7-18/h4-9,13-14,16H,2-3,10-12H2,1H3/t16-/m1/s1

InChI key: InChIKey=KFHYZKCRXNRKRC-MRXNPFEDSA-N

SMILES: C(CN1[C@H](C)CCC1)C2=CC=3C(O2)=CC=C(C3)C4=CC=C(C#N)C=C4

Synonyms:

• Benzonitrile, 4-[2-[2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl]-5-benzofuranyl]-
• ABT 239
• 4-[2-[2-[(2R)-2-Methyl-1-pyrrolidinyl]ethyl]-5-benzofuranyl]benzonitrile
• (R)-4-[2-[2-(2-Methylpyrrolidinyl)ethyl]benzofuran-5-yl]benzonitrile

(R)-4-(2-(2-(2-methylpyrrolidin-1-yl)ethyl)benzofuran-5-yl)benzonitrile

CAS: 460746-46-7

Formula: C₂₂H₂₂N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 330.4229

Ref: IN-DA00DBAP

ABT-239

CAS: 460746-46-7

ABT-239

Purity: ≥98%

Molecular weight: 330.42g/mol

Ref: 54-BUP09114

ABT-239

CAS: 460746-46-7

ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 receptor (H3R) antagonists.

Formula: C₂₂H₂₂N₂O

Purity: 99.94%

Color and Shape: Solid

Molecular weight: 330.42

Ref: TM-T14087