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CAS 460751-66-0

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5-Bromo-N-Fmoc-L-tryptophan

Description:
5-Bromo-N-Fmoc-L-tryptophan is a derivative of the amino acid tryptophan, characterized by the presence of a bromine atom at the 5-position of the indole ring and a Fmoc (9-fluorenylmethoxycarbonyl) protecting group on the amino group. This compound is typically used in peptide synthesis and research due to its ability to facilitate the formation of peptide bonds while protecting the amine functionality. The Fmoc group is particularly advantageous because it can be easily removed under mild basic conditions, allowing for subsequent reactions without damaging sensitive functional groups. The bromine substitution can enhance the compound's reactivity and influence its biological properties, making it useful in various biochemical applications. Additionally, 5-Bromo-N-Fmoc-L-tryptophan can serve as a building block in the synthesis of more complex peptides and proteins, contributing to studies in pharmacology and molecular biology. Its unique structural features make it a valuable tool in the development of novel therapeutic agents and in the exploration of tryptophan's role in biological systems.
Formula:C26H21BrN2O4
Synonyms:
  • 5-Bromo-N-Fmoc-L-tryptophan
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl L-Trp(5-Br)-OH
  • Fmoc-L-5-BromoTryptophan
  • (2S)-3-(5-bromo-1H-indol-3-yl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
  • (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-bromo-1H-indol-3-yl)propanoic acid
  • 5-Bromo-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tryptophan
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