CAS 461-88-1

2,4-Diaminopyridine

Description:

2,4-Diaminopyridine (CAS 461-88-1) is an organic compound characterized by its pyridine ring substituted with two amino groups at the 2 and 4 positions. It appears as a white to light yellow crystalline solid and is soluble in water and organic solvents, reflecting its polar nature due to the presence of amino groups. This compound is primarily known for its role as a pharmaceutical agent, particularly in the treatment of certain neurological disorders, such as Lambert-Eaton myasthenic syndrome, where it enhances neurotransmitter release. 2,4-Diaminopyridine acts as a potassium channel blocker, which can increase the release of acetylcholine at the neuromuscular junction. Additionally, it has applications in research and development, particularly in studies related to nerve regeneration and muscle function. However, it must be handled with care due to potential toxicity and side effects, including cardiovascular and neurological impacts. Proper safety measures should be observed when working with this compound in laboratory settings.

Formula: C₅H₇N₃

InChI: InChI=1S/C5H7N3/c6-4-1-2-8-5(7)3-4/h1-3H,(H4,6,7,8)

InChI key: InChIKey=IFFLKGMDBKQMAH-UHFFFAOYSA-N

SMILES: NC=1C=C(N)N=CC1

Synonyms:

• 2,4-Diaminopyridine
• 2,4-Pyridinediamine
• Pyridine, 2,4-diamino-
• Pyridine-2,4-Diamine

pyridine-2,4-diamine

CAS: 461-88-1

Formula: C₅H₇N₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 109.1292

Ref: IN-DA003U2B

2,4-Diaminopyridine

CAS: 461-88-1

2,4-Diaminopyridine

Purity: 99%

Molecular weight: 109.13g/mol

Ref: 54-OR90697

Minodronic Acid Impurity 10

CAS: 461-88-1

Formula: C₅H₇N₃

Molecular weight: 109.13

Ref: 4Z-M-093015

2,4-Pyridinediamine

Controlled Product

CAS: 461-88-1

Applications 2,4-Pyridinediamine was studies for its interaction with cholinesterase inhibitors, neostigmine (N390010) and edrophonium (E336000) as a combined treatment for the restoration of muscle contraction. Experiments have shown the doses of neostigmine and edrophonium could be halved when they were combined with a small small amount of 2,4-pyridinediamine without apparent loss of antagonistic potency.
References Requena, J., et al.: J. Gen. Physiol., 85, 789 (1985); Biessels, P.T.M., et al.: Euro. J. Pharmacol., 106, 319 (1984); Den, H., et al.: Euro. J. Pharmacol., 94, 353 (1983); Biessels, P.T.M., et al.: Arch. Int. Pharmacodyn. Ther., 293, 228 (1988);

Formula: C₅H₇N₃

Color and Shape: Neat

Molecular weight: 109.13

Ref: TR-P991510

Pyridine-2,4-diamine

CAS: 461-88-1

Formula: C₅H₇N₃

Purity: 98%

Color and Shape: Solid, Brown powder

Molecular weight: 109.132

Ref: 10-F077272