CAS 461-96-1

1-Bromo-3,5-difluorobenzene

Description:

1-Bromo-3,5-difluorobenzene is an aromatic halogenated compound characterized by the presence of a bromine atom and two fluorine atoms attached to a benzene ring. Its molecular formula is C6H3BrF2, indicating that it contains six carbon atoms, three hydrogen atoms, one bromine atom, and two fluorine atoms. This compound typically appears as a colorless to pale yellow liquid with a distinctive aromatic odor. It is known for its relatively low solubility in water but is soluble in organic solvents such as ethanol and ether. The presence of halogen substituents significantly influences its chemical reactivity, making it useful in various applications, including as an intermediate in organic synthesis and in the production of pharmaceuticals and agrochemicals. Additionally, 1-bromo-3,5-difluorobenzene exhibits properties such as moderate volatility and stability under standard conditions, although it may undergo reactions typical of halogenated compounds, such as nucleophilic substitution or electrophilic aromatic substitution. Safety precautions should be taken when handling this substance due to its potential toxicity and environmental impact.

Formula: C₆H₃BrF₂

InChI: InChI=1S/C6H3BrF2/c7-4-1-5(8)3-6(9)2-4/h1-3H

InChI key: InChIKey=JHLKSIOJYMGSMB-UHFFFAOYSA-N

SMILES: BrC1=CC(F)=CC(F)=C1

Synonyms:

• 1,3-Difluoro-5-bromobenzene
• 1-Brom-3,5-difluorbenzol
• 1-Bromo-3,5-Difluoro-Benzene
• 3,5-Difluoro bromobenzene
• 3,5-Difluoro-1-Bromobenzene
• 3,5-DifluoroBrmorobenzene
• 3,5-Difluorobromobenzene
• 3,5-Difluorophenyl bromide
• 5-Bromo-1,3-difluorobenzene
• Benzene, 1-bromo-3,5-difluoro-
• 1-Bromo-3,5-difluorobenzene

1-Bromo-3,5-difluorobenzene

CAS: 461-96-1

Formula: C₆H₃BrF₂

Purity: >98.0%(GC)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 192.99

Ref: 3B-B1764

1-Bromo-3,5-difluorobenzene, 98%

CAS: 461-96-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₃BrF₂

Purity: 98%

Color and Shape: Clear, colorless to pale yellow, Liquid

Molecular weight: 192.99

Ref: 02-A14053

1-Bromo-3,5-Difluorobenzene

CAS: 461-96-1

Formula: C₆H₃BrF₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 192.9888

Ref: IN-DA0032PL

3,5-Difluorobromobenzene

CAS: 461-96-1

3,5-Difluorobromobenzene

Formula: C₆H₃BrF₂

Purity: 98%

Color and Shape: clear. colourless liquid

Molecular weight: 192.99g/mol

Ref: 54-PC1385

1-Bromo-3,5-difluorobenzene

CAS: 461-96-1

Formula: C₆H₃BrF₂

Molecular weight: 192.99

Ref: 7W-GK6153

1-Bromo-3,5-difluorobenzene, min. 99%

CAS: 461-96-1

Formula: C₆H₃BrF₂

Purity: min. 99%

Color and Shape: Clear, colorless to pale-yellow liquid

Molecular weight: 192.99

Ref: 08-09-0055

1-Bromo-3,5-difluorobenzene

CAS: 461-96-1

Formula: C₆H₃BrF₂

Purity: 98.0%

Color and Shape: Liquid

Molecular weight: 192.991

Ref: 10-F001416

1-Bromo-3,5-difluorobenzene

Controlled Product

CAS: 461-96-1

Applications 1-Bromo-3,5-difluorobenzene is used in the synthesis of selective antagonists of GluN2C/GluN2D is used in the synthesis of COX-2 inhibitors as anti-inflammatory agents and anti-cancer agents.
References Khanna, I. et al.: J. Med. Chem., 40, 1634 (1997); Pommery, N. et al.: J. Med. Chem., 47, 6195 (2004);

Formula: C₆H₃BrF₂

Color and Shape: Neat

Molecular weight: 192.99

Ref: TR-B683440