CAS: 461054-93-3 - (3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester

Formula: C₂₆H₃₅N₃O₅

InChI: InChI=1/C26H35N3O5/c1-14(2)11-20-23-17(16-8-7-15(33-6)12-19(16)27-23)13-21-24(31)28-18(25(32)29(20)21)9-10-22(30)34-26(3,4)5/h7-8,12,14,18,20-21,27H,9-11,13H2,1-6H3,(H,28,31)/t18-,20-,21-/m0/s1

Synonyms:

• Pyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid, 1,2,3,4,6,7,12,12a-octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxo-, 1,1-dimethylethyl ester, (3S,6S,12aS)-
• tert-Butyl 3-[(3S,6S,12aS)-6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-3-yl]propanoate
• tert-butyl 3-[(3S,6S,12aS)-9-methoxy-6-(2-methylpropyl)-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-3-yl]propanoate

Ko143 hydrate

CAS: 461054-93-3

• Formula: C₂₆H₃₅N₃O₅·xH₂O
• Purity: ≥ 98.0%
• Color and Shape: White to off-white powder
• Molecular weight: 469.57 (anhydrous)

Ko 143

CAS: 461054-93-3

Ko 143 is a selective inhibitor of ATP-binding cassette sub-family G member 2 (ABCG2; BCRP).

• Formula: C₂₆H₃₅N₃O₅
• Purity: 99.89%
• Color and Shape: Solid
• Molecular weight: 469.57

KO 143

CAS: 461054-93-3

• Formula: C₂₆H₃₅N₃O₅
• Color and Shape: Neat
• Molecular weight: 469.573

KO 143

CAS: 461054-93-3

KO 143 is a methyltransferase inhibitor that blocks the activity of p-glycoprotein. It has been …

• Formula: C₂₆H₃₅N₃O₅
• Purity: Min. 95%
• Molecular weight: 469.57 g/mol