CAS 4611-05-6

Ophiobolin A

Description:

Ophiobolin A is a natural compound classified as a sesterterpene, primarily derived from certain species of fungi, particularly those in the genus Ophiobolus. It is characterized by its complex molecular structure, which includes a unique arrangement of carbon, hydrogen, and oxygen atoms. Ophiobolin A exhibits notable biological activity, particularly in its ability to inhibit cell division and exhibit cytotoxic effects against various cancer cell lines. This compound has garnered interest in the field of medicinal chemistry for its potential therapeutic applications. Additionally, Ophiobolin A has been studied for its effects on plant growth and development, showcasing its role as a phytotoxin. Its mechanism of action involves interference with cellular processes, making it a subject of research in both pharmacology and toxicology. The compound is typically isolated through extraction and purification methods from its natural sources, and its study contributes to the understanding of natural products in drug discovery and development.

Formula: C₂₅H₃₆O₄

InChI: InChI=1S/C25H36O4/c1-15(2)10-18-11-16(3)25(29-18)9-8-23(4)12-19-22(20(27)13-24(19,5)28)17(14-26)6-7-21(23)25/h6,10,14,16,18-19,21-22,28H,7-9,11-13H2,1-5H3/t16-,18-,19-,21+,22+,23+,24+,25-/m0/s1

InChI key: InChIKey=MWYYLZRWWNBROW-ISPAKYAGSA-N

SMILES: C[C@@H]1[C@@]2([C@]3([C@](C)(CC2)C[C@]4([C@@](C(C=O)=CC3)(C(=O)C[C@@]4(C)O)[H])[H])[H])O[C@@H](C=C(C)C)C1

Synonyms:

• (+)-Ophiobolin A
• (2′S,3′S,3aR,5′R,6aS,9R,9aS,10aR)-1,3a,4,4′,5′,6a,7,8,9,9a,10,10a-Dodecahydro-9-hydroxy-3′,9,10a-trimethyl-5′-(2-methyl-1-propen-1-yl)-7-oxospiro[dicyclopenta[a,d]cyclooctene-3(2H),2′(3′H)-furan]-6-carboxaldehyde
• (7E)-3-hydroxy-5-oxo-14,18-epoxyophiobola-7,19-dien-25-al
• (7E,18R)-3-hydroxy-5-oxo-14,18-epoxyophiobola-7,19-dien-25-al
• Cochliobolin
• Cochliobolin A
• NSC 114340
• Ophiobola-7,19-dien-25-al, 14,18-epoxy-3-hydroxy-5-oxo-, (18R)-
• Ophiobolin
• Ophiobolin, Helminthosporium sp.
• Spiro[dicyclopenta[a,d]cyclooctene-3(2H),2′(3′H)-furan]-6-carboxaldehyde, 1,3a,4,4′,5′,6a,7,8,9,9a,10,10a-dodecahydro-9-hydroxy-3′,9,10a-trimethyl-5′-(2-methyl-1-propen-1-yl)-7-oxo-, (2′S,3′S,3aR,5′R,6aS,9R,9aS,10aR)-
• Spiro[dicyclopenta[a,d]cyclooctene-3(2H),2′(3′H)-furan]-6-carboxaldehyde, 1,3a,4,4′,5′,6a,7,8,9,9a,10,10a-dodecahydro-9-hydroxy-3′,9,10a-trimethyl-5′-(2-methyl-1-propenyl)-7-oxo-, (2′S,3′S,3aR,5′R,6aS,9R,9aS,10aR)-

Ophiobolin A (Cochliobolin A)

CAS: 4611-05-6

Ophiobolin A (Cochliobolin A)

Molecular weight: 400.55094g/mol

Ref: 54-BI12142

Ophiobolin A

CAS: 4611-05-6

Ophiobolin A: Fungal metabolite, phytotoxin, inhibits calmodulin-activated phosphodiesterase (IC50: 9μM), with antimicrobial and anticancer properties.

Formula: C₂₅H₃₆O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 400.559

Ref: TM-T16397

Ophiobolin A

CAS: 4611-05-6

Formula: C₂₅H₃₆O₄

Molecular weight: 400.6

Ref: 7W-GA7678

Ophiobolin A

CAS: 4611-05-6

Ophiobolin A

Formula: C₂₅H₃₆O₄

Purity: By hplc: 98.75% (Typical Value in Batch COA)

Color and Shape: white powder

Molecular weight: 400.55g/mol

Ref: 54-BIM0137

Ophiobolin A

CAS: 4611-05-6

M05736 - Ophiobolin A

Formula: C₂₅H₃₆O₄

Purity: 98.76%

Molecular weight: 400.559

Ref: 10-M05736