CAS 461432-26-8
:Dapagliflozin
Description:
Dapagliflozin is a medication primarily used in the management of type 2 diabetes mellitus. It belongs to the class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors, which work by preventing the reabsorption of glucose in the kidneys, thereby promoting its excretion in urine and lowering blood glucose levels. The chemical formula of dapagliflozin is C21H25ClO6S, and it features a sulfonyl group, a chlorophenyl moiety, and a glucose-like structure that facilitates its mechanism of action. Dapagliflozin is typically administered orally and is often prescribed in conjunction with other antidiabetic agents to enhance glycemic control. In addition to its glucose-lowering effects, it has been associated with weight loss and a reduction in blood pressure. Common side effects may include urinary tract infections and genital mycotic infections due to increased glucose in the urine. Overall, dapagliflozin represents a significant advancement in diabetes treatment, offering a unique approach to managing blood sugar levels.
Formula:C21H25ClO6
InChI:InChI=1S/C21H25ClO6/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18-,19+,20-,21+/m1/s1
InChI key:InChIKey=JVHXJTBJCFBINQ-ADAARDCZSA-N
SMILES:O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O)C2=CC(CC3=CC=C(OCC)C=C3)=C(Cl)C=C2
Synonyms:- (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-<span class="text-smallcaps">D</span>-glucitol
- (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol
- (1S)-1,5-anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-D-glucitol
- <span class="text-smallcaps">D</span>-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-
- Bms-512148
- D-Glucitol, 1,5-Anhydro-1-C-[4-Chloro-3-[(4-Ethoxyphenyl)Methyl]Phenyl]-, (1S)-
- Dapagliflozin
- Dapagliflozin free base
- (2S,3R,4R,5S,6R)-2-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
