CAS: 461443-59-4 - Aplaviroc

Formula: C₃₃H₄₃N₃O₆

InChI: InChI=1S/C33H43N3O6/c1-2-3-19-36-30(38)28(29(37)24-7-5-4-6-8-24)34-32(41)33(36)17-20-35(21-18-33)22-23-9-13-26(14-10-23)42-27-15-11-25(12-16-27)31(39)40/h9-16,24,28-29,37H,2-8,17-22H2,1H3,(H,34,41)(H,39,40)/t28-,29-/m1/s1

InChI key: InChIKey=GWNOTCOIYUNTQP-FQLXRVMXSA-N

SMILES: O=C(O)C1=CC=C(OC2=CC=C(C=C2)CN3CCC4(C(=O)NC(C(=O)N4CCCC)C(O)C5CCCCC5)CC3)C=C1

Synonyms:

• 4-[4-[[(3R)-1-Butyl-3-[(R)-cyclohexylhydroxymethyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl]methyl]phenoxy]benzoic acid
• Ak 602
• Aplaviroc
• Apliviroc
• Benzoic acid, 4-[4-[[(3R)-1-butyl-3-[(R)-cyclohexylhydroxymethyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl]methyl]phenoxy]-
• Benzoic acid, 4-[4-[[1-butyl-3-[(R)-cyclohexylhydroxymethyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl]methyl]phenoxy]-
• Gsk 873140
• Gw 873140
• Ono 4128

Aplaviroc

CAS: 461443-59-4

Inhibits chemokine receptor CCR5; anti-viral activity against HIV

• Formula: C₃₃H₄₃N₃O₆
• Purity: Min. 95%
• Molecular weight: 577.71 g/mol

Aplaviroc

CAS: 461443-59-4

Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist. With IC50s of 0.1-0.4 nM …

• Formula: C₃₃H₄₃N₃O₆
• Purity: 98.78% - 99.53%
• Color and Shape: Solid
• Molecular weight: 577.71