CAS 461640-33-5

Acetyl-(N-Me-Leu¹⁷,N-Me-Phe¹⁹)-Amyloid β-Protein (16-20) amide

CAS: 461640-33-5

Membrane-permeable inhibitor of Aβ (1-40) fibrillogenesis.

Formula: C₃₉H₅₉N₇O₆

Purity: 98.7%

Color and Shape: White Lyophilisate

Molecular weight: 721.94

Ref: 01-4095735

Ac-Lys-(Me)Leu-Val-(Me)Phe-Phe-NH2 trifluoroacetate salt

CAS: 461640-33-5

Formula: C₃₉H₅₉N₇O₆·xC₂HF₃O₂

Molecular weight: 721.93 (free base b

Ref: 7W-GL6507

Ac-Lys-N-Me-Leu-Val-N-Me-Phe-Phe-NH2

CAS: 461640-33-5

Ac-Lys-N-Me-Leu-Val-N-Me-Phe-Phe-NH2 is a peptide that has been shown to inhibit the formation of amyloid fibrils in Alzheimer's Disease. Ac-Lys-N-Me-Leu-Val-N-Me-Phe (KLVFF) is a biologically active peptide that is membrane permeable, allowing it to cross the blood brain barrier and enter the central nervous system. It inhibits the fibrillogenesis of amyloid beta protein, preventing it from aggregating into plaques.

Formula: C₃₉H₅₉N₇O₆

Purity: Min. 95%

Molecular weight: 721.95 g/mol

Ref: 3D-PAB-3631-PI

Ac-Lys-(Me)Leu-Val-(Me)Phe-Phe-NH2

CAS: 461640-33-5

Ac-Lys-(Me)Leu-Val-(Me)Phe-Phe-NH2 is a synthetic chemokine that is a member of the CXC subfamily. Chemokines are small proteins that have a hydrophobic region, which allows them to insert into membranes. This chemokine has been shown to be capable of forming dimers in the presence of other chemokines and exhibits a high degree of homology with congener chemokines. The Ac-Lys-(Me)Leu-Val-(Me)Phe-Phe-NH2 sequence has been shown to denature at pH 8 and has water solubility; however, it does not dissolve in lipid bilayers such as phospholipid bilayers or monolayers. The Ac-Lys-(Me)Leu-Val-(Me)Phe-Phe-NH2 sequence is also stable in an Alzheimer's disease mouse model.

Formula: C₃₉H₅₉N₇O₆

Purity: Min. 95%

Molecular weight: 721.93 g/mol

Ref: 3D-FA110201