CAS 462-20-4

Dihydrolipoic acid

Description:

Dihydrolipoic acid, also known as 1,2-dithiolane-3-pentanoic acid, is a naturally occurring compound that serves as a potent antioxidant. It is a reduced form of alpha-lipoic acid, which is a cofactor in mitochondrial bioenergetics and plays a crucial role in cellular metabolism. Dihydrolipoic acid is characterized by its ability to scavenge free radicals and regenerate other antioxidants, such as vitamins C and E, enhancing their efficacy. The compound is soluble in both water and lipids, allowing it to exert its effects in various biological environments. Its structure features a dithiolane ring, which is essential for its redox properties. Dihydrolipoic acid has been studied for its potential therapeutic applications, including neuroprotection, anti-inflammatory effects, and support in metabolic disorders. Additionally, it may contribute to the management of conditions related to oxidative stress. Overall, dihydrolipoic acid is recognized for its multifaceted role in promoting health and mitigating oxidative damage at the cellular level.

Formula: C₈H₁₆O₂S₂

InChI: InChI=1S/C8H16O2S2/c9-8(10)4-2-1-3-7(12)5-6-11/h7,11-12H,1-6H2,(H,9,10)

InChI key: InChIKey=IZFHEQBZOYJLPK-UHFFFAOYSA-N

SMILES: C(C(CCS)S)CCCC(O)=O

Synonyms:

• (±)-Dihydro-α-lipoic acid
• 6,8-Dimercaptooctanoic acid
• 6,8-Disulfanyloctanoic Acid
• 6,8-Dithiooctanoic acid
• <span class="text-smallcaps">DL</span>-Dihydro-α-lipoic acid
• DL-a-Lipoic Acid, Dihydro-
• Dihydrolipoate
• Dihydrolipoic acid
• Dihydrothioctic acid
• Lipoic acid, dihydro-
• Octanoic acid, 6,8-dimercapto-
• Reduced lipoic acid
• Reduced thioctic acid
• Thioctic acid, dihydro-
• Usaf Xr-12
• dl-Dihydro-alpha-6-thioctic acid
• dl-Dihydrolipoic acid
• α-Lipoic acid, dihydro-
• γ-Lipoic acid

Dihydrolipoic Acid

CAS: 462-20-4

Formula: C₈H₁₆O₂S₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 208.3414

Ref: IN-DA00DE0P

Dihydrolipoic acid

CAS: 462-20-4

Dihydrolipoic acid

Purity: ≥95%

Molecular weight: 208.34g/mol

Ref: 54-BUP14181

6,8-Dimercaptooctanoic Acid

CAS: 462-20-4

6,8-Dimercaptooctanoic Acid

Purity: 97%

Molecular weight: 208.34g/mol

Ref: 54-OR1011972

Thioctic Acid Impurity 2

CAS: 462-20-4

Formula: C₈H₁₆O₂S₂

Color and Shape: Yellow Oil

Molecular weight: 208.33

Ref: 4Z-T-886

Dihydrolipoic Acid

CAS: 462-20-4

Formula: C₈H₁₆O₂S₂

Purity: >97.0%(GC)(T)

Color and Shape: Colorless to Light orange to Yellow clear liquid to slightly cloudy liquid

Molecular weight: 208.33

Ref: 3B-D4586

Gamma-Lipoic Acid

Controlled Product

CAS: 462-20-4

Applications γ-Lipoic Acid, is a metabolite of α-Lipoic Acid (L468730), which is a over-the-counter nutritional supplements, that has been used as antioxidant. It is also fat-metabolism stimulator, and thus used a "weight loss" and "energy" supplement.
References Plotzker, R., et al.: Am. J. Med. Sci., 283, 79 (1982), Evans, J., et al.: Diabetes Technol. Ther., 2, 401 (2000), Konrad, D., et al.: Diabetes, 50, 1464 (2001), Lockhart, B., et al.: Brain Res., 855, 292 (2000),

Formula: H₂O(C₈H₁₄OS₂)n

Color and Shape: Neat

Molecular weight: 208.3414

Ref: TR-L468755

Lipoic acid, reduced

CAS: 462-20-4

Lipoic acid, reduced (LAR) is a naturally occurring compound that is found in many living organisms. It has been used to study the mechanisms of DNA binding and protein oxidation. Lipoic acid, reduced has been shown to have anti-inflammatory properties by inhibiting the production of prostaglandins. The rate constant for LAR is 10-3 M-1s-1 at 25°C and pH 7.0, which can be measured using a polymer composition method. This compound also has an optical sensor and chemiluminescence method that are able to measure the rate constant and determine its concentration.

Formula: C₈H₁₆O₂S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 208.34 g/mol

Ref: 3D-FL29290

DIHYDROLIPOIC ACID

CAS: 462-20-4

Purity: 97%

Molecular weight: 208.3300018

Ref: 10-F792202

6,8-Dimercaptooctanoic acid

CAS: 462-20-4

Formula: C₈H₁₆O₂S₂

Molecular weight: 208.33

Ref: ST-EA-CP-T110006

Dihydrolipoic acid

CAS: 462-20-4

Dihydrolipoic acid (USAF XR-12), a dithiol carboxylic acid, is a potent antioxidant active against various reactive oxygen species at 0.01-0.5 mM.

Formula: C₈H₁₆O₂S₂

Purity: 97.51%

Color and Shape: Yellow To Orange Liquid

Molecular weight: 208.34

Ref: TM-T21233