CAS 4621-66-3

Thionicotinamide

Description:

Thionicotinamide, with the CAS number 4621-66-3, is a chemical compound that is a derivative of nicotinamide, featuring a sulfur atom in its structure. This compound is characterized by its thioamide functional group, which imparts distinct chemical properties compared to its parent compound. Thionicotinamide is typically a white to off-white crystalline solid, soluble in water and various organic solvents, making it versatile for different applications. It is known for its potential biological activities, including antioxidant properties and possible roles in cellular metabolism. Additionally, thionicotinamide may exhibit effects on enzyme activity and has been studied for its implications in pharmacology and biochemistry. Its stability and reactivity can be influenced by environmental factors such as pH and temperature. As with many chemical substances, safety precautions should be observed when handling thionicotinamide, as it may pose health risks if ingested or improperly managed. Overall, thionicotinamide is a compound of interest in both research and potential therapeutic applications.

Formula: C₆H₆N₂S

InChI: InChI=1/C6H6N2S/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

InChI key: InChIKey=XQWBMZWDJAZPPX-UHFFFAOYSA-N

SMILES: C(N)(=S)C=1C=CC=NC1

Synonyms:

• 3-(Aminothiocarbonyl)pyridine
• 3-Pyridinecarbothioamide
• 3-Pyridinethiocarboxamide
• 3-Pyridylthioformamide
• 3-Thioamidopyridine
• 3-Thiocarbamoylpyridine
• NSC 18336
• Nicotinamide, thio-
• Nicotinic acid thioamide
• Nicotinothioamide
• Pyridine-3-carbothioamide
• Pyridine-3-thiocarboxamide
• Sr 4336
• Thio-3-pyridinecarboxamide
• Thionicotinamide
• AKOS B028584
• 3-PYRIDYLTHIOCARBOXAMIDE
• PYRIDINE-3-CARBOTHIOIC ACID AMIDE
• Nicotinthioamide
• Thionicotinamide,98%
• PYRIDINE-3-THIOCARBOXAMIDE (THIONICOTINAMIDE)
• PYRIDINE-3-THIOAMIDE
• thio-nicotinamid

Thionicotinamide

CAS: 4621-66-3

Formula: C₆H₆N₂S

Purity: >98.0%(T)(HPLC)

Color and Shape: Light yellow to Yellow to Green powder to crystal

Molecular weight: 138.19

Ref: 3B-T0765

3-Pyridinecarbothioamide

CAS: 4621-66-3

Formula: C₆H₆N₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 138.1902

Ref: IN-DA00I8KH

Pyridine-3-carbothioamide

CAS: 4621-66-3

Pyridine-3-carbothioamide

Purity: 98%

Molecular weight: 138.19g/mol

Ref: 54-OR28672

Pyridine-3-carbothioic acid amide

CAS: 4621-66-3

Formula: C₆H₆N₂S

Purity: 98%

Color and Shape: Solid

Molecular weight: 138.19

Ref: 10-F021345

Thionicotinamide

CAS: 4621-66-3

Thionicotinamide is a drug that belongs to the group of ethionamide. It is a synthetic compound with synergistic activity against tuberculosis bacteria. Thionicotinamide inhibits bacterial growth by binding to mycolic acid, which is a component of the cell wall. Thionicotinamide also has conformational properties, which inhibit the enzyme activities. This drug also interacts with other drugs, such as ethionamide, and may have an effect on the metabolism of these drugs in humans. Thionicotinamide binds to lipids and reduces the activity of enzymes that are involved in lipid synthesis. The nitrogen atoms of thionicotinamide bind to four oxygen atoms from two molecules of glycol ethers in a 1:1 ratio. This binding leads to the formation of hydrogen bonds between these molecules, resulting in an increase in kinetic energy for these reactions and improved structural analysis for this molecule.

Formula: C₆H₆N₂S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 138.19 g/mol

Ref: 3D-FT36203