CAS 463-00-3

γ-Guanidinobutyric acid

Description:

γ-Guanidinobutyric acid (GBA), with the CAS number 463-00-3, is a naturally occurring amino acid derivative that plays a role in various biological processes. It is characterized by its guanidine group, which contributes to its basicity and ability to participate in hydrogen bonding. GBA is a non-proteinogenic amino acid, meaning it is not incorporated into proteins but can influence metabolic pathways. It is known for its potential role as a precursor to creatine, which is vital for energy metabolism in muscle cells. The substance is typically found in trace amounts in the human body and can be synthesized from other amino acids. GBA has garnered interest for its potential therapeutic applications, including its effects on exercise performance and cognitive function. In terms of physical properties, it is a white crystalline solid that is soluble in water, making it suitable for various formulations. Its stability and reactivity can be influenced by pH and temperature, which are important considerations in its handling and application in research and industry.

Formula: C₅H₁₁N₃O₂

InChI: InChI=1S/C5H11N3O2/c6-5(7)8-3-1-2-4(9)10/h1-3H2,(H,9,10)(H4,6,7,8)

InChI key: InChIKey=TUHVEAJXIMEOSA-UHFFFAOYSA-N

SMILES: C(CNC(=N)N)CC(O)=O

Synonyms:

• 2-[(Diaminomethylidene)Amino]Butanoic Acid
• 4-Guanidinobutanoic acid
• 4-[(Aminoiminomethyl)amino]butanoic acid
• 4-[(Diaminomethylidene)Amino]Butanoic Acid
• Butanoic acid, 4-((aminoiminomethyl)amino)- (9CI)
• Butanoic acid, 4-[(aminoiminomethyl)amino]-
• Butyric acid, 4-guanidino-
• Hl 6450
• N-(4-Butanoic acid)guanidine
• Nsc 521717
• gamma-Guanidinobutyrate
• γ-Guanidinebutyric acid
• γ-Guanidinobutyric acid

Butanoic acid,4-[(aminoiminomethyl)amino]-

CAS: 463-00-3

Formula: C₅H₁₁N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 145.1597

Ref: IN-DA0072S2

4-Guanidinobutanoic acid

CAS: 463-00-3

4-Guanidinobutanoic acid

Purity: 98%

Molecular weight: 145.16g/mol

Ref: 54-OR1011545

4-Guanidinobutanoic acid

CAS: 463-00-3

4-Guanidinobutanoic acid

Purity: ≥98%

Molecular weight: 145.16g/mol

Ref: 54-BUP17498

4-Guanidinobutyric acid

CAS: 463-00-3

Molecular weight: 145.16

Ref: 7W-GM5345

4-Guanidinobutanoic acid

CAS: 463-00-3

4-Guanidinobutanoic acid (4-GBA) is an L-arginine metabolite that has been used in the intestinal transport tranport studies. It has been use to hPAT1.

Formula: C₅H₁₁N₃O₂

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 145.16

Ref: TM-T4927

4-Guanidinobutanoic Acid-d6

Controlled Product

CAS: 463-00-3

Applications 4-Guanidinobutanoic Acid-D6 is an isotopic labeled compound of 4-Guanidinobutanoic acid (G825100). 4-Guanidinobutanoic acid is a guanidine derivative and a metabolite a found in urine, synthesized by gut microbiota.
References Yu, C.; et al.: Biomed. Chromatogr., 32 (2018); Lin, Z.; et al.: Scientific Reports, 8, 1 (2018).

Formula: C₅D₆H₅N₃O₂

Color and Shape: Neat

Molecular weight: 151.197

Ref: TR-G825102

4-Guanidinobutanoic acid

CAS: 463-00-3

Purity: 98%

Color and Shape: Solid

Molecular weight: 145.1620026

Ref: 10-F614441

4-Guanidinobutanoic acid

CAS: 463-00-3

4-Guanidinobutanoic acid is a metabolite of creatine that is excreted in the urine. The metabolic profiles of 4-guanidinobutanoic acid have been determined in rat kidneys and compared to other metabolites, such as creatinine, gamma-aminobutyric acid, and urea nitrogen. Chronic exposure to 4-guanidinobutanoic acid leads to an increase in urea nitrogen and creatinine levels. It also causes a decrease in enzyme activities and uptake of creatine by the kidney. 4-Guanidinobutanoic acid has not shown any toxic effects on the kidney or any other organ system at concentrations up to 1000 mg/kg body weight per day.

Formula: C₅H₁₁N₃O₂

Purity: Min. 95%

Molecular weight: 145.16 g/mol

Ref: 3D-AAA46300