CAS 4641-57-0

1-Phenyl-2-pyrrolidinone

Description:

1-Phenyl-2-pyrrolidinone, with the CAS number 4641-57-0, is an organic compound characterized by its pyrrolidinone structure, which features a five-membered lactam ring. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its purity and temperature. It is known for its moderate polarity, which allows it to dissolve in various organic solvents while being less soluble in water. The presence of both a phenyl group and a pyrrolidinone moiety contributes to its unique chemical reactivity, making it a valuable intermediate in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. Additionally, 1-Phenyl-2-pyrrolidinone exhibits potential biological activity, which has garnered interest in medicinal chemistry. Its stability under standard conditions and ability to participate in various chemical reactions, such as nucleophilic substitutions and cyclizations, further enhance its utility in synthetic applications. However, as with many organic compounds, proper handling and safety precautions are essential due to potential health hazards associated with exposure.

Formula: C₁₀H₁₁NO

InChI: InChI=1S/C10H11NO/c12-10-7-4-8-11(10)9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2

InChI key: InChIKey=JMVIVASFFKKFQK-UHFFFAOYSA-N

SMILES: O=C1N(CCC1)C2=CC=CC=C2

Synonyms:

• 1-Phenyl-2-pyrrolidone
• 1-Phenylpyrrolidin-2-One
• 2-Pyrrolidinone, 1-phenyl-
• N-Phenyl-2-pyrrolidinone
• N-Phenyl-2-pyrrolidone
• N-Phenylbutyrolactam
• NSC 25325
• 1-Phenyl-2-pyrrolidinone

1-Phenyl-2-pyrrolidone

CAS: 4641-57-0

Formula: C₁₀H₁₁NO

Purity: >99.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 161.20

Ref: 3B-P0319

1-Phenyl-2-pyrrolidinone, 99%

CAS: 4641-57-0

A novel derivative of 1-phenyl-2-pyrrolidinone, blebbistatin, inhibits non-muscle myocin II activity with high specificity. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand.

Formula: C₁₀H₁₁NO

Purity: 99%

Color and Shape: Crystals or powder or crystalline powder or granules or fused solid, Colorless to white to pale cream or pale yellow or pale pink

Molecular weight: 161.20

Ref: 02-L14660

1-Phenylpyrrolidin-2-one

CAS: 4641-57-0

Formula: C₁₀H₁₁NO

Purity: 97%

Color and Shape: Solid

Molecular weight: 161.2004

Ref: IN-DA003EM3

1-Phenylpyrrolidin-2-one

CAS: 4641-57-0

1-Phenylpyrrolidin-2-one

Purity: 98%

Molecular weight: 161.20g/mol

Ref: 54-OR930513

1-Phenyl-2-pyrrolidinone

CAS: 4641-57-0

1-Phenyl-2-pyrrolidinone is a chemical compound that is used in the synthesis of pharmaceuticals and other organic compounds. It is prepared by the Friedel-Crafts reaction between an amide and methyl anthranilate, or by reacting amines with phospotungstic acid. 1-Phenyl-2-pyrrolidinone can be reacted with epoxides to form butyrolactones, which are used in the production of antibiotics such as butyric acid. The reaction mechanism for 1-phenyl-2-pyrrolidinone involves an alpha hydrogen abstraction from a pi bond followed by a beta hydrogen abstraction from another pi bond. This process leads to a free radical intermediate that reacts with oxygen to form phenol, which then undergoes a second oxidation step to form the desired product.

Formula: C₁₀H₁₁NO

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 161.2 g/mol

Ref: 3D-FP71860

1-Phenyl-2-pyrrolidone

Controlled Product

CAS: 4641-57-0

Applications 1-Phenyl-2-pyrrolidone (cas# 4641-57-0) is a compound useful in organic synthesis.

Formula: C₁₀H₁₁NO

Color and Shape: Neat

Molecular weight: 161.08

Ref: TR-P336770

1-Phenyl-2-pyrrolidinone

CAS: 4641-57-0

Formula: C₁₀H₁₁NO

Purity: 95%

Color and Shape: Solid, Crystalline

Molecular weight: 161.204

Ref: 10-F075213