CAS 4643-58-7

Verrucarin J

Description:

Verrucarin J is a chemical compound classified as a macrocyclic lactone and is part of the verrucarin family, which are known for their biological activity. It is produced by certain species of fungi, particularly those in the genus Myrothecium. This compound exhibits notable antifungal and cytotoxic properties, making it of interest in pharmaceutical research. Verrucarin J has a complex structure characterized by multiple rings and functional groups, contributing to its biological activity. It is soluble in organic solvents but has limited solubility in water. The compound has been studied for its potential applications in cancer treatment and as a tool in molecular biology due to its ability to inhibit protein synthesis. Safety and handling precautions are necessary when working with Verrucarin J, as it may pose health risks. Overall, its unique structure and biological properties make it a significant subject of study in the field of natural products and medicinal chemistry.

Formula: C₂₇H₃₂O₈

InChI: InChI=1/C27H32O8/c1-17-8-10-26-15-32-24(30)13-18(2)9-11-31-22(28)6-4-5-7-23(29)35-19-14-21(34-20(26)12-17)27(16-33-27)25(19,26)3/h4-7,12-13,19-21H,8-11,14-16H2,1-3H3/b6-4+,7-5-,18-13+/t19-,20-,21-,25-,26-,27+/m1/s1

InChI key: InChIKey=GXCGYHWSYNQVHU-VWFRAIFSSA-N

SMILES: C[C@]12[C@@]3([C@@]4(O[C@]5([C@@]1(CCC(C)=C5)COC(=O)/C=C(/C)\CCOC(=O)\C=C\C=C\C(=O)O[C@@]2(C4)[H])[H])[H])CO3

Synonyms:

• (1'R,2S,3'R,8'R,12'E,18'E,20'Z,24'R,25'S)-5',13',25'-Trimethyl-11'H,17'H,22'H-spiro[oxirane-2,26'-[2,10,16,23]tetraoxatetracyclo[22.2.1.0~3,8~.0~8,25~]heptacosa[4,12,18,20]tetraene]-11',17',22'-trione
• (2′E)-2′,3′-Didehydro-2′-deoxyverrucarin A
• 4643-58-7
• Muconomycin B
• Spiro[16,18-methano-1H,3H,23H-[1,6,12]trioxacyclooctadecino[3,4-d][1]benzopyran-17(18H),2′-oxirane], verrucarin A deriv.
• Verrucarin A, 2′,3′-didehydro-2′-deoxy-, (2′E)-
• Verrucarin J

Verrucarin J

CAS: 4643-58-7

Verrucarin J

Formula: C₂₇H₃₂O₈

Purity: By hplc: 100% (Typical Value in Batch COA)

Color and Shape: white powder

Molecular weight: 484.54g/mol

Ref: 54-BIV1007

Verrucarin J

CAS: 4643-58-7

Verrucarin J, a Myrothecium fungus metabolite, triggers apoptosis in some cancer cells and fights Candida, Mucor, and JUNV (IC50: 1.2 ng/mL).

Formula: C₂₇H₃₂O₈

Color and Shape: Solid

Molecular weight: 484.54

Ref: TM-T69225