CAS 465-22-5

Scillarenin

Description:

Scillarenin, with the CAS number 465-22-5, is a glycoside derived from the plant species Scilla maritima, commonly known as sea onion. It is classified as a cardiac glycoside, which means it has the ability to influence heart function. Scillarenin exhibits a structure characterized by a steroid nucleus with a sugar moiety, typically contributing to its biological activity. This compound is known for its potential therapeutic effects, particularly in the treatment of heart conditions, as it can enhance cardiac contractility and modulate heart rhythm. However, like other cardiac glycosides, it has a narrow therapeutic window and can be toxic at higher doses. Scillarenin's solubility properties are influenced by its glycosidic nature, affecting its absorption and distribution in biological systems. Its pharmacological profile includes both positive inotropic effects and potential side effects, necessitating careful monitoring when used in clinical settings. Overall, scillarenin represents an important compound in the study of cardiac pharmacology and natural product chemistry.

Formula: C₂₄H₃₂O₄

InChI: InChI=1S/C24H32O4/c1-22-10-7-17(25)13-16(22)4-5-20-19(22)8-11-23(2)18(9-12-24(20,23)27)15-3-6-21(26)28-14-15/h3,6,13-14,17-20,25,27H,4-5,7-12H2,1-2H3/t17-,18+,19-,20+,22-,23+,24-/m0/s1

InChI key: InChIKey=OVUOVMIMOCJILI-KFZANIOBSA-N

SMILES: O[C@@]12[C@@](C)([C@H](CC1)C=3C=CC(=O)OC3)CC[C@]4([C@]2(CCC=5[C@]4(C)CC[C@H](O)C5)[H])[H]

Synonyms:

• (3Beta,17Xi)-3,14-Dihydroxybufa-4,20,22-Trienolide
• (3Beta,8Xi,9Xi)-3,14-Dihydroxybufa-4,20,22-Trienolide
• (3β)-3,14-Dihydroxybufa-4,20,22-trienolide
• 3β-Scillarenin
• Bufa-4,20,22-trienolide, 3,14-dihydroxy-, (3β)-
• Bufa-4,20,22-trienolide, 3β,14-dihydroxy-
• Cardiogenin
• NSC 234669
• Scillarenin
• Scillarenin A
• Scillarenine

Scillarenin

CAS: 465-22-5

Scillarenin (3β-Scillarenin) is a plant steroid lactone isolated from D. maritima, with antiviral activity, used in the study of viral infections.

Formula: C₂₄H₃₂O₄

Color and Shape: Solid

Molecular weight: 384.51

Ref: TM-T124831

Scillarenin

Controlled Product

CAS: 465-22-5

Applications Scillarenin is a bufadienolide derivative that acts as a cardiotonic agent. A metabolite of Meproscillarin.
References Rietbrock, N. et al.: Eur. J. Clin. Pharmacol., 8, 427 (1975); Shamovskii, I.L. et al.: Bioorg. Khim., 9, 1112 (1983); Hammarstroem, L. et al.: Mol. Immunol., 17, 463 (1980);

Formula: C₂₄H₃₂O₄

Color and Shape: Neat

Molecular weight: 384.51

Ref: TR-S199960

Scillarenin

Controlled Product

CAS: 465-22-5

Aglycone of Proscillaridin A

Formula: C₂₄H₃₂O₄

Purity: Min. 95%

Molecular weight: 384.51 g/mol

Ref: 3D-XS173207