CAS 465-90-7

Hellebrigenin

Description:

Hellebrigenin, with the CAS number 465-90-7, is a chemical compound classified as a steroidal alkaloid. It is primarily derived from plants in the family Ranunculaceae, particularly from the genus Helleborus. This compound exhibits a range of biological activities, including potential anti-inflammatory and analgesic properties, which have garnered interest in pharmacological research. Hellebrigenin is characterized by its complex molecular structure, which includes multiple rings typical of steroid compounds. Its solubility properties can vary, often being more soluble in organic solvents than in water. The compound's stability and reactivity can be influenced by environmental factors such as pH and temperature. Due to its bioactive nature, Hellebrigenin is studied for its potential therapeutic applications, although further research is needed to fully understand its mechanisms of action and efficacy in clinical settings. As with many natural products, the extraction and purification processes are crucial for obtaining this compound in a usable form for research and potential medicinal applications.

Formula: C₂₄H₃₂O₆

InChI: InChI=1S/C24H32O6/c1-21-8-5-18-19(6-10-23(28)12-16(26)4-9-22(18,23)14-25)24(21,29)11-7-17(21)15-2-3-20(27)30-13-15/h2-3,13-14,16-19,26,28-29H,4-12H2,1H3/t16-,17+,18-,19+,21+,22-,23-,24-/m0/s1

InChI key: InChIKey=TVKPTWJPKVSGJB-XHCIOXAKSA-N

SMILES: C(=O)[C@@]12[C@@]3([C@]([C@]4(O)[C@](C)(CC3)[C@H](CC4)C=5C=CC(=O)OC5)(CC[C@]1(O)C[C@@H](O)CC2)[H])[H]

Synonyms:

• (3Beta,5Beta)-3,5,14-Trihydroxy-19-Oxobufa-20,22-Dienolide
• (3Beta,5Beta,8Xi,9Xi)-3,5,14-Trihydroxy-19-Oxobufa-20,22-Dienolide
• (3β,5β)-3,5,14-Trihydroxy-19-oxobufa-20,22-dienolide
• 19-Oxo-3-beta,5,14-trihydroxy-5-beta-bufa-20,22-dienolide
• 5-beta-Bufa-20,22-dienolide, 3-beta,5,14-trihydroxy-19-oxo-
• 5β-Bufa-20,22-dienolide, 3β,5,14-trihydroxy-19-oxo-
• Brn 0056259
• Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)-
• Bufotalidin
• Gellebrigenin
• Hellebrigenin
• Nsc 89594
• Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3β,5β)-

Hellebrigenin

CAS: 465-90-7

Hellebrigenin

Purity: ≥98%

Molecular weight: 416.51g/mol

Ref: 54-BUP22154

Bufotalidin

CAS: 465-90-7

Formula: C₂₄H₃₂O₆

Molecular weight: 416.51

Ref: 7W-GY2993

Hellebrigenin

CAS: 465-90-7

Hellebrigenin,Selective inhibitor of MAPK pathways (ERK, p38, JNK) and XIAP. Suppresses Akt expression/phosphorylation. Activates apoptosis pathways.

Formula: C₂₄H₃₂O₆

Purity: 99.98%

Color and Shape: Solid

Molecular weight: 416.51

Ref: TM-TN1728

Bufotalidin

CAS: 465-90-7

Formula: C₂₄H₃₂O₆

Purity: 95%~99%

Molecular weight: 416.514

Ref: BP-BP4193

Bufotalidin

CAS: 465-90-7

Bufotalidin is a caffeic acid derivative that has been shown to have inhibitory properties on the heart and locomotor activity. Bufotalidin was shown to decrease the cardiac contractility of isolated rat hearts by inhibiting calcium influx. It also inhibits basic protein kinase C (PKC) in HL-60 cells, which may be due to its ability to inhibit PKC translocation from the cytosol to the membrane. Bufotalidin also has an inhibitory effect on autophagy, which is a process that breaks down cellular components. The molecular mechanisms underlying these effects are not yet understood.

Formula: C₂₄H₃₂O₆

Purity: Min. 95%

Molecular weight: 416.51 g/mol

Ref: 3D-AAA46590